A8MQX3 · ESF12_ARATH
- ProteinEMBRYO SURROUNDING FACTOR 1.2
- GeneESF1.2
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids
- Protein existenceEvidence at transcript level
- Annotation score4/5
Function
function
Maternally-contributed central cell peptide regulating suspensor development and correct auxin distribution in early developing embryos.
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Biological Process | embryonic axis specification | |
Biological Process | suspensor development |
Keywords
- Molecular function
Names & Taxonomy
Protein names
- Recommended nameEMBRYO SURROUNDING FACTOR 1.2
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionA8MQX3
Proteomes
Organism-specific databases
Genome annotation databases
Phenotypes & Variants
Disruption phenotype
No visible phenotype, due to redundancy with ESF1.1 and ESF1.3. Simultaneous down-regulation of all 3 genes by RNAi induces embryo abnormalities.
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 16 variants from UniProt as well as other sources including ClinVar and dbSNP.
PTM/Processing
Features
Showing features for signal, chain, disulfide bond.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-23 | |||||
Sequence: MKSQTVLISIFIFSFFALHQCMQ | ||||||
Chain | PRO_0000430060 | 24-82 | EMBRYO SURROUNDING FACTOR 1.2 | |||
Sequence: MDVGEIEGSNKISIGKCVPAQCSVSFFKRDCWCCFRDQSMCSKTQKECESNPRCPPLKF | ||||||
Disulfide bond | 40↔56 | |||||
Sequence: CVPAQCSVSFFKRDCWC | ||||||
Disulfide bond | 45↔77 | |||||
Sequence: CSVSFFKRDCWCCFRDQSMCSKTQKECESNPRC | ||||||
Disulfide bond | 54↔71 | |||||
Sequence: CWCCFRDQSMCSKTQKEC | ||||||
Disulfide bond | 57↔64 | |||||
Sequence: CFRDQSMC |
Keywords
- PTM
Proteomic databases
Expression
Tissue specificity
Expressed exclusively in ovule embryo sacs and in early developing endosperms.
Developmental stage
Primarily expressed in the central cell gamete of nonfrtilized ovules, which upon fertilization gives rise to the endosperm, and later in the micropylar endosperm, which surrounds the embryo.
Gene expression databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Sequence similarities
Belongs to the MEG family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Sequence processingThe displayed sequence is further processed into a mature form.
- Length82
- Mass (Da)9,386
- Last updated2007-12-04 v1
- Checksum5220AD5518826E30
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AC007354 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AC009398 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
CP002684 EMBL· GenBank· DDBJ | AEE28640.1 EMBL· GenBank· DDBJ | Genomic DNA |