A8K6C1 · A8K6C1_HUMAN

  • Protein
    Cholesteryl ester transfer protein
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    3/5

Function

function

Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL.

Catalytic activity

GO annotations

AspectTerm
Cellular Componenthigh-density lipoprotein particle
Molecular Functioncholesterol transfer activity
Molecular Functionlipid binding
Biological Processcholesterol metabolic process
Biological Processhigh-density lipoprotein particle remodeling
Biological Processreverse cholesterol transport
Biological Processtriglyceride transport
Biological Processvery-low-density lipoprotein particle remodeling

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Cholesteryl ester transfer protein

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo

Accessions

  • Primary accession
    A8K6C1

Subcellular Location

Secreted
Note: Secreted in plasma.

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for signal, chain, disulfide bond.

TypeIDPosition(s)Description
Signal1-17
ChainPRO_501521905818-493Cholesteryl ester transfer protein
Disulfide bond160↔201

Keywords

Proteomic databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain31-258Lipid-binding serum glycoprotein N-terminal
Domain272-476Lipid-binding serum glycoprotein C-terminal

Sequence similarities

Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    493
  • Mass (Da)
    54,780
  • Last updated
    2007-12-04 v1
  • Checksum
    16D47A02C99B07EC
MLAATVLTLALLGNAHACSKGTSHEAGIVCRITKPALLVLNHETAKVIQTAFQRASYPDITGEKAMMLLGQVKYGLHNIQISHLSIASSQVELVEAKSIDVSIQNVSVVFKGTLKYGYTTAWWLGIDQSIDFEIDSAIDLQINTQLTCDSGRVRTDAPDCYLSFHKLLLHLQGEREPGWIKQLFTNFISFTLKLVLKGQICKEINVISNIMADFVQTRAASILSDGDIGVDISLTGDPVITAPYLESHHKGHFIYKNVSEDLPLPTFSPTLLGDSRMLYFWFSERVFHSLAKVAFQDGRLMLSLMGDEFKAVLETWGFNTNQEIFQEVVGGFPSQAQVTVHCLKMPKISCQNKGVVVNSSVMVKFLFPRPDQQHSVAYTFEEDIVTTVQASYSKKKLFLSLLDFQITPKTVSNLTESSSESIQSFLQSMITAVGIPEVMSRLEVVFTALMNSKGVSLFDIINPEIITRDGFLLLQMDFGFPEHLLVDFLQSLS

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AK291586
EMBL· GenBank· DDBJ
BAF84275.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

Disclaimer

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