A8J6Z4 · A8J6Z4_9ACTN

Function

Cofactor

pantetheine 4'-phosphate (UniProtKB | Rhea| CHEBI:47942 )

Features

Showing features for active site.

137235001,0001,5002,0002,5003,0003,500
TypeIDPosition(s)Description
Active site2530Proton acceptor; for dehydratase activity
Active site2702Proton donor; for dehydratase activity

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Cellular Componentplasma membrane
Molecular Function3-oxoacyl-[acyl-carrier-protein] synthase activity
Molecular Functionfatty acid synthase activity
Molecular Functionoxidoreductase activity
Molecular Functionphosphopantetheine binding
Molecular Functionzinc ion binding
Biological ProcessDIM/DIP cell wall layer assembly
Biological Processfatty acid biosynthetic process
Biological Processmacrolide biosynthetic process

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • Modular polyketide synthase

Gene names

    • Name
      nemA1-2

Organism names

Accessions

  • Primary accession
    A8J6Z4

Subcellular Location

PTM/Processing

Keywords

Family & Domains

Features

Showing features for domain, region.

Type
IDPosition(s)Description
Domain33-466Ketosynthase family 3 (KS3)
Region468-489Disordered
Region919-938Disordered
Region1184-1210Disordered
Domain1483-1558Carrier
Domain1577-2004Ketosynthase family 3 (KS3)
Region2498-2624N-terminal hotdog fold
Domain2498-2781PKS/mFAS DH
Region2641-2781C-terminal hotdog fold
Region2889-2908Disordered
Domain3566-3641Carrier

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    3,723
  • Mass (Da)
    394,394
  • Last updated
    2007-12-04 v1
  • MD5 Checksum
    C3694A5EAC1D6F3D2A8E2F6CF0205806
MENEEKLLDYLKWVTADLHRSRERVTELEEAGREPIAIVGMACRFPGEVRSPEELWGLVASGGDAIGAFPDDRGWDLDGLFDPDPERAGTSYTRRGGFLYDAAEFDAGFFGISPREAMAMDPQQRLLLETSWEAFERAGIDPSSVRGSRVGVFAGLMYHDYAAAQGSTGDGDGEPDFEGYLGDGSVSSIASGRIAYTLGLAGAAITVDTACSSSLVALHLACQALRTGDSELALAGGVSVMSTPRTFVQFSRQRGLSADGRCKAYAAAADGTGFSEGVGMVLVERLSDARRLGHPVLAVVRGSAVNQDGASNGLTAPNGPSQERVIREALANAGLTAADVDAVEGHGTGTRLGDPIELQALLATYGQGRARERPLWLGSVKSNIGHAQAAAGVGGVIKMVMALRHGELPRTLHVDAPSPRVDWSAGEVRLLTEAVAWPAAADGEPRRAGVSSFGVSGTNAHVILEEAPASEGEEAPPPEPGSPLPWVVSGHSEAGLRAQAQALAEFARTAPGAELVDVGAALARGRAALGHRAVVVASEREEFERALAALACGEPHPCVVDGSADGRREDGVVFVFPGQGGQWAGMGLDLLTTSGVFAEHIGACERALAPWVEWSLTEMLHREAEDPVWERADIVQPVLFSVMVSLAALWRSYGIEPDAVVGHSQGEIAAAHVCGALTLEDAAKVVALRSRALAALRGRGGMVSLSLSTADAGELVERRWAGRLWVAALNGPEATTVSGDVDALEELLAHCAKSEVRARRVPVDYASHCPHTEAIAEEIVDSLGDITPRAATVPFYSTVDDMWLDTTRLDASYWYRNLRLPVRFSQAVRALTEEGHRLFIETSPHPTLVPAIEDHGDVTALGTLRRHGDDTERFLTALAHLHVTGAAGQDLWRHHYARLRPAPRHVDLPTYPFQRRRYWLEKPDPQTRPQRSRSTAPDLDRLEAEFWQAVEETDTDTLAHTLHLDTQTLEPVLPALATWHQQQRDHARINTWTYQETWKPLHLPTTRPTTPTSWLIAIPETHRNHPHTTNLLTNLPHHNITPIPLTINHTTDLHHAYHHAHHHTTPPITAVLSLLALDETPHPHHPHTPTGTLLNLTLTQTHTQTHPPTPLWYLTTQATTTHPNDPLTHPTQAQTIGLARTTHLEHPHHTGGHIDLPTTPHPNTLTQLITALTHPHHQHNLTIRTHTTHTRRLTPTTLQPTTPTPPTNPHGTTLITGGTGALATTLAHHLATTGTQHLLLTSRRGPHTPGARQLHTQLTQLGTNTTITACDLSDPDQLTHLLTHIPPEHPLTTVIHTAGILDDATLTNLTPTQLDNVLRAKAHTAHLLHHATLHTPLDHFVLYSSAAATLGAPGQANYAAANAYLDALAHHRHTHNLPATTIAWGTWQGNGLADSDKARANLDRRGFLPMPETLAAAAAVRAIESRRPSVVIAAIDWARAERTPDVEDLLPAADEGSSSGKPEAAPVDLRGTLSRQSAADQQATLLGLVRTQAAVVLRHTEPEALAPGQAFRALGFDSLTAVELRNRLAKATDLALPASLVFDHPTPVKLAEFLRTELLGTAPATTAAVPALQAHTDEPIAIIGMACRFPGAVTTPEHLWNLIATEQDAIGEFPTDRGWDLDNLYHPDPDHPGTTYTRHGGFLHDAGDFDADFFGINPREALAMDPQQRLLLETAWEAIEHAGILPDALHGTPTGVFTGVNAQDYAAHTHTSPHTTEGYTLTGTAGSIASGRIAYVLGLEGPAVTIDTACSSSLVALHLACQALRAGECTTALASGISIMTTPLAFTEFSRQRGLAADGRCKAFAAAADGTGWSEGVGTLLLERLSDAERNGHRVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQALVNANLSAVDVDAVEAHGTGTKLGDPIEAQALLATYGQGRAQEQPLWLGSVKSNLGHTQAAAGMAGLIKMVMALRHESLPRTLHVDEPSPEVDWSSGAVSLLTEARPWPRVEDRPRRAGVSSFGVSGTNAHVIVEEAPAPTGVEAVEAAPAGVETAAAAAVVVETDGAGRVSADLPLVWVASGKSQAAIRAQAAALHAHVLDHPEQDADDIGYSLATTRALFDHRATLIAPDRHTVPEPLTGLGDGRTHPHLIPTPPTEPGHTHKIAFLCSGQGTQRPGMATGLYHTYPAFAAALDETCAHFDPHLDHPLHDLLLNHDPTDLLTHTLYAQPALFTLQKALHHLITETYGITPHYLAGHSLGEITAAHLAGILTLPDATHLITTRARLMQTMPPGTMTTLHTTPEHIQPLLDQHPGKAAIAAVNSPHSLVISGDPDTIHHITTTCHNQGITTKPLATNHAFHSPHTDTILEQLDTTTHTLTYHQPHTPLITSTPGDPLTPHYWTHQTRQPVHWTDTIHTLHTHGVTTYIALGPEHTLTTLTHHNVPHHQPTAITLTHPHHNPTHHLLTALAHLHTTQPTGPNIWHHHYTPVAPAPRHVDLPTYPFPRRRYWVQASAGTGDVSAAGLQRPDHPLLGAVMELADGDGIVLTGRLSLHTHPWLADHSVGGVALLPGTALLELAFQAGLRAGCPGVDELTLHAPLVVPESGHVVVQVSVSVPGEAGRRGVSVYGRLVEDGGLEGEWTRHAEGVVCPSVPGESVVVEPVADGVWPPSGAQPVDLEEFYGRLAGGGFVYGPVFQGLCAAWRDGDDVVAEVRLPDEGLADVAGFGVHPALLDAAVQAVTLLFPDQQQAGLAAHTWNGVSLHARGATVLRLRMTPTDATSTAVRLHATDETGAPVLTLDSLLMRPVPLEGLGAGVRRGSLFELGWVPVEGMPASVAGGGGELVAWECPGGGVAEVTAAALGVVQEWLADEREGDARLVVVTRGAVAVDAGEPVRDVAGAAVWGLVRSAQSEHPDRFALLDLDPDTKTDPGIDTDGDTDVSADAKVGTGDGLDDAAVASALARGESQLAVRDGVVRVARLGGLVGGLSLPGGVGWRLDGGGSGLLEGVGVVASDAAGVVLGRGQVRVAVRAAGVNFRDVLVALGMVPGQVGVGSEGAGVVVEVGPGVEGLVVGDRVFGVFGDAFAPVVVAQEVLLARIPEGWSFAQAASVPVVFATAYLGLVDLAGVRRGESVLVHAAAGGVGTAAVQLARHLGAEVYATASEAKWARLRAAGVAPQRIASSRSVEFESRFRRASGGRGVDVVLNCLAGEYTDASLRLCSPQGGRFLELGKTDIRDAGEVAARFPGVSYRAYDLMDAGAQRVGEILHTVVDLFRRGVLEPLPVTAWDVRQAHQALRSMRSGLHVGKNVLTLPVPLDAEGTVLVTGGTGTLGAAVARHLAAGHGVRHLLLVSRRGMAAAGAEKLCAELGQAGVSVSVAGCDVADRAQVAALLEQVPAEHPLTAVVHTAGVLDDATVTCLDRNKIDAVLGAKVDGALHLHELTAGMDLSAFVLFSSAAGVLGSPGQGNYAAANAALDALAHQRRAAGLPALSLAWGLWEEASGMTGHLDAADRHRITRSGLHPLTTPDALALLDTALAAGRPALLPADLRPTHPAPPLLEHLAPARTSHRTAHTSTATGVGQDVSLTDRLATLTPEQRHDTLLALARTHIAAVLGHPSPDTIDPERTFRDLGFDSLTAVELRNRLTRATGLRLPATLAFDHPTPTALTHHLTTLLNPNDNDNVGPVLMELERLESALAALDRDDSACERVTLRLQSLMLRWSGSERQSAENTDDSSRFASATAEELLEFIDRDLGLS

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AB363939
EMBL· GenBank· DDBJ
BAF85838.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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