A8J6X7 · PCDP1_CHLRE
- ProteinCilia- and flagella-associated protein 221 homolog
- GeneCFAP221
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids645 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score4/5
Function
function
May play a role in cilium morphogenesis.
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | 9+2 motile cilium | |
Cellular Component | axoneme | |
Molecular Function | calmodulin binding | |
Biological Process | cilium assembly | |
Biological Process | cilium movement | |
Biological Process | motile cilium assembly |
Keywords
- Molecular function
- Biological process
Names & Taxonomy
Protein names
- Recommended nameCilia- and flagella-associated protein 221 homolog
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Chlorophyta > core chlorophytes > Chlorophyceae > CS clade > Chlamydomonadales > Chlamydomonadaceae > Chlamydomonas
Accessions
- Primary accessionA8J6X7
Subcellular Location
UniProt Annotation
GO Annotation
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000395001 | 1-645 | Cilia- and flagella-associated protein 221 homolog | |||
Sequence: MALASNPRRRLHEVRVQKYVVIAVTWRGAQPMSQRARPSRVVRAAAWGMFARCHPGAAAGWHRCTDLVTRSSARPAYTVASQSFSQGLVEDAPLQNPNTLTYNRVYSKVGNTRILQAEPAVLNFGGYELGKVYSQVLRIRNVRASGTRFHIIPPSTPFFKATCPAKKGLLAPGMTEEVAVEFCPTQYRYYYDCVRVHCEEENLLIPLHAYPVANEALFPTRVDFGRVALGQEVVRSHTLECKVPVDFEYEIVEVKPNPAFRVEPARGVVPGRGRVTVDMWFCPLALTTEEAVIETEVAGVYVPDTMLLSAAEVGLRTKDVRGAIEARKAAAAEQQAALEKGALFRLQLALAEEAARKVALGTAPHSGQQLLTAEQPELEAGGAVHQPSAPVGSSSSGGGGGSDPAFKPEHKRTRVLDKFMRAVWRVVTHQRLQRRLERIKEVLAHLGYDKQRLAEEAANPVLLVSESDRPGTAPTKYLRPEMVRVRPLPLYRDVLFQVHHATDLSHYTDFDELAPFTSKVRERLVPSGLVPPLSDYPTMPDACKNMPYITLEIGNRYGDDRVYGAPDPSYSPYGSLDVDYAVQPRQYDVYDSARHEAVASGGVRSLRGGPGLSDSWLVRQICPAVPTDEQLAKCGGTGIVNTIPN |
Proteomic databases
Interaction
Subunit
Interacts with calmodulin; calcium-dependent. Part of the PDCP1 complex composed of CFAP46, CFAP54, CFAP74 and CFAP221; the PDCP1 complex binds calmodulin.
Structure
Family & Domains
Features
Showing features for region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 381-408 | Disordered | ||||
Sequence: GGAVHQPSAPVGSSSSGGGGGSDPAFKP | ||||||
Region | 428-435 | Interaction with calmodulin | ||||
Sequence: THQRLQRR |
Sequence similarities
Belongs to the PCDP1 family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length645
- Mass (Da)71,053
- Last updated2007-12-04 v1
- Checksum3C668D66C212509E