A8J0N6 · DRC10_CHLRE
- ProteinDynein regulatory complex protein 10
- GeneDRC10
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids356 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
function
Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes (PubMed:23427265, PubMed:25411337).
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | axoneme | |
Cellular Component | motile cilium |
Names & Taxonomy
Protein names
- Recommended nameDynein regulatory complex protein 10
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Chlorophyta > core chlorophytes > Chlorophyceae > CS clade > Chlamydomonadales > Chlamydomonadaceae > Chlamydomonas
Accessions
- Primary accessionA8J0N6
Proteomes
Genome annotation databases
Subcellular Location
UniProt Annotation
GO Annotation
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000444020 | 1-356 | Dynein regulatory complex protein 10 | |||
Sequence: MNSLEAGRVLSVLDEALEGIRLISYVTQDVLDTAEQLRDMLGEDLANALIKHRQLIQSAKSTLNNDQVQASTLELVRLLKKSPSAQRLQVLPYERTYGILQTLQYFEQLRQFAQKRLTTTVEEDSSNREFFEEVRDREERAVAEQEQLKQKLKLQRVELQKAAGTIQVSEDRARGEVSEVQSSTQQSRAAIEGSARAQSEADKSSFQSDLDQVTKELAAARAELARLRQEHKDNEALLRKARKRAEQDVEVQIGEYDADVGAKEEELGKARAEYEEVLRQLQEYNSGWSEMYQERLEYEERERRLADQRFQAALLAVRQNHAARVIQSYWRGFKKAREAAKKKAKKLEKAKAAKKK |
Proteomic databases
Structure
Family & Domains
Features
Showing features for coiled coil, region, compositional bias, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Coiled coil | 126-167 | |||||
Sequence: SNREFFEEVRDREERAVAEQEQLKQKLKLQRVELQKAAGTIQ | ||||||
Region | 173-209 | Disordered | ||||
Sequence: ARGEVSEVQSSTQQSRAAIEGSARAQSEADKSSFQSD | ||||||
Compositional bias | 178-209 | Polar residues | ||||
Sequence: SEVQSSTQQSRAAIEGSARAQSEADKSSFQSD | ||||||
Coiled coil | 197-287 | |||||
Sequence: AQSEADKSSFQSDLDQVTKELAAARAELARLRQEHKDNEALLRKARKRAEQDVEVQIGEYDADVGAKEEELGKARAEYEEVLRQLQEYNSG | ||||||
Domain | 319-348 | IQ | ||||
Sequence: QNHAARVIQSYWRGFKKAREAAKKKAKKLE |
Sequence similarities
Belongs to the DRC10 family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length356
- Mass (Da)40,926
- Last updated2007-12-04 v1
- Checksum0444028A66A5C831
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 178-209 | Polar residues | ||||
Sequence: SEVQSSTQQSRAAIEGSARAQSEADKSSFQSD |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
DS496131 EMBL· GenBank· DDBJ | EDP01996.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CM008963 EMBL· GenBank· DDBJ | PNW87558.1 EMBL· GenBank· DDBJ | Genomic DNA |