A8HYJ1 · TOC34_CHLRE

Function

function

GTPase involved in protein precursor import into chloroplasts. Seems to recognize chloroplast-destined precursor proteins and regulate their presentation to the translocation channel through GTP hydrolysis (By similarity).
Functions as an essential component of the outer chloroplast membrane translocon (TOC) complex, which, in turn, catalyzes the import of nucleus-encoded precursor polypeptides from the cytoplasm to the chloroplast (PubMed:23167510).

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Binds 1 Mg2+ ion by subunit.

Features

Showing features for binding site.

139750100150200250300350
TypeIDPosition(s)Description
Binding site102-107GTP (UniProtKB | ChEBI)
Binding site106Mg2+ (UniProtKB | ChEBI)
Binding site121-126GTP (UniProtKB | ChEBI)
Binding site228GTP (UniProtKB | ChEBI)
Binding site271-272GTP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentchloroplast outer membrane
Molecular FunctionGTP binding
Molecular Functionhydrolase activity
Molecular Functionmetal ion binding
Biological Processprotein transport

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Translocase of chloroplast 34 homolog, chloroplastic
  • EC number
  • Short names
    Cr-TOC34
    ; TOC34p

Gene names

    • Name
      TOC34
    • ORF names
      CHLREDRAFT_187290

Organism names

Accessions

  • Primary accession
    A8HYJ1

Genome annotation databases

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane329-349Helical

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004425321-397Translocase of chloroplast 34 homolog, chloroplastic

Proteomic databases

Interaction

Subunit

Homodimer, heterodimer with other TOC proteins, and monomer. Part of the TOC core complex that includes 1 protein for the specific recognition of transit peptides surrounded by a ring composed of four proteins forming translocation channels, and four to five GTP-binding proteins providing energy. This core complex can interact with components of the TIC complex to form a larger import complex (By similarity).
Interacts with ARSA1 (PubMed:28382961).

Family & Domains

Features

Showing features for region, compositional bias, domain, motif.

TypeIDPosition(s)Description
Region1-72Disordered
Compositional bias11-63Acidic residues
Domain90-321AIG1-type G
Region99-106G1
Region121-124Homodimerization
Region126-130G2
Region155-158G3
Region193-198Homodimerization
Region227-230G4
Region271-273G5
Motif350-358AKR2A-binding sequence (ABS) required for chloroplast outer envelope membrane targeting

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    397
  • Mass (Da)
    44,542
  • Last updated
    2007-12-04 v1
  • Checksum
    2A4AD399A5939A3C
MAQPPRPAEEYDDDVQEDEDELKEGELDDDESHEAASEGGEAAAGDEEAEDDEQDEEDGDEDSQPWAGLNRLPERDDMLDILNELRAEGRKQLTVLLLGKSSVGKSSLINSLLGEAVVRVQAFKLQADTDITTTVVRQVAVGNSEVDGFRLKLIDTCGLEDPEAGDTVNLGALSKIAEDVRGVGIDVVLYCDRLDLYRVDPLDKAIIDAISSTFGRGIWRRTVVALTHANLVQTPPGTDYDSFVNGRVRLIRGAVRGPLFFRPSLPVALVENSETCPVSSESGFRVLPDGEPWLVALVSQLVDMAAARRRPYKYHPRLSSKPSHRFRWLLPVAIAAEVLFYRRFLHPRLDDNQRRVEREEERVWALRGQQRRALGLHRPHRPDKDAAWRLEQMYDDD

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias11-63Acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
GU814014
EMBL· GenBank· DDBJ
ADF43133.1
EMBL· GenBank· DDBJ
Genomic DNA
DS496110
EMBL· GenBank· DDBJ
EDP08621.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp