A8HME3 · IFT22_CHLRE

Function

function

Component of the intraflagellar transport (IFT) complex B. Functions in regulating the cellular pool size of both complex A and complex B and thus plays a critical role in determining the cellular availability of IFT particles.

Caution

Although similar to the small GTPase superfamily, lacks the conserved catalytic Gln in position 67 which is replaced by a Ser residue, possibly explaining the weak GTPase activity. In contrast to other members of the family, it is not prenylated (PubMed:22076686) and unlikely to associate directly with membranes.

Features

Showing features for binding site.

119220406080100120140160180
TypeIDPosition(s)Description
Binding site12-19GTP (UniProtKB | ChEBI)
Binding site62-69GTP (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentmotile cilium
Molecular FunctionGTP binding

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Intraflagellar transport protein 22
  • Alternative names
    • Flagellar-associated protein 9

Gene names

    • Name
      FAP9
    • ORF names
      CHLREDRAFT_195877

Organism names

Accessions

  • Primary accession
    A8HME3

Genome annotation databases

Subcellular Location

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004294201-192Intraflagellar transport protein 22

Proteomic databases

Interaction

Subunit

Component of the IFT complex B, composed of IFT88, IFT70, IFT52, IFT46, IFT27, IFT25 and IFT22.

Family & Domains

Sequence similarities

Belongs to the small GTPase superfamily. Rab family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    192
  • Mass (Da)
    21,343
  • Last updated
    2007-12-04 v1
  • Checksum
    138EEC1B70A9C700
MAEHGLKIAVVGPQRTGKTLLCRALAEQPILLGEMSYQPTAAVRIQEISRVLGIDRVKVQFWDVSGSVQYQSYWPVLAKEVDGLLMVIDPNRPEQERDLETFYRNFAEPNNLYTRQCMVMAIQVQKEGGGLGGWQGLQGGLKKLSQSYVAINPANPAAGVQEAYSHLDVLFQGALQSKKEALESSYMNQEDQ

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
DS496108
EMBL· GenBank· DDBJ
EDP09407.1
EMBL· GenBank· DDBJ
Genomic DNA
EF593954
EMBL· GenBank· DDBJ
ABU90456.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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