A8GAJ0 · PPNP_SERP5
- ProteinPyrimidine/purine nucleoside phosphorylase
- GeneppnP
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids
- Protein existenceInferred from homology
- Annotation score4/5
Function
function
Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.
Catalytic activity
- a purine D-ribonucleoside + phosphate = a purine nucleobase + alpha-D-ribose 1-phosphate
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | deoxyuridine phosphorylase activity | |
Molecular Function | guanosine phosphorylase activity | |
Molecular Function | purine-nucleoside phosphorylase activity | |
Molecular Function | thymidine phosphorylase activity | |
Molecular Function | uridine phosphorylase activity |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePyrimidine/purine nucleoside phosphorylase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Yersiniaceae > Serratia
Accessions
- Primary accessionA8GAJ0
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_1000068736 | 1-96 | Pyrimidine/purine nucleoside phosphorylase | |||
Sequence: MLKVNEYFAGKVKSIGFDSSSIGLTSVGVMEEGEYTFTTALPEEMTVITGALKVLLPGSPDWQVFMPGEKFFVPAHSEFNLQVADATAYLCRYLSK |
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length96
- Mass (Da)10,534
- Last updated2007-11-13 v1
- Checksum805BD282CFC2B86A
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP000826 EMBL· GenBank· DDBJ | ABV40130.1 EMBL· GenBank· DDBJ | Genomic DNA |