A7YG54 · A7YG54_MUSNI

Function

function

Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.

Cofactor

Protein has several cofactor binding sites:
heme b (UniProtKB | Rhea| CHEBI:60344 )

Note: Binds 2 heme groups non-covalently.
heme (UniProtKB | Rhea| CHEBI:30413 )

Note: Binds 2 heme groups non-covalently.

Features

Showing features for binding site.

137950100150200250300350
TypeIDPosition(s)Description
Binding site83Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue
Binding site97Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue
Binding site182Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue
Binding site196Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue
Binding site201a ubiquinone (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentmitochondrial inner membrane
Cellular Componentrespiratory chain complex III
Molecular Functionmetal ion binding
Molecular Functionubiquinol-cytochrome-c reductase activity
Biological Processrespiratory electron transport chain

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Cytochrome b

Gene names

    • Name
      cytb
    • Synonyms
      CYB
      , cyt-b
      , CYTB
      , cytochrome b
    • ORF names
      MnivalisMt_p013

Encoded on

  • Mitochondrion

Organism names

  • Taxonomic identifier
  • Strains
    • 79252
    • 79255
    • 79304
    • 02-0224
    • Mn23m0403
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Carnivora > Caniformia > Musteloidea > Mustelidae > Mustelinae > Mustela

Accessions

  • Primary accession
    A7YG54

Subcellular Location

Membrane
; Multi-pass membrane protein
Mitochondrion inner membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane30-52Helical
Transmembrane87-107Helical
Transmembrane113-133Helical
Transmembrane140-158Helical
Transmembrane178-200Helical
Transmembrane229-246Helical
Transmembrane288-307Helical
Transmembrane319-338Helical
Transmembrane350-372Helical

Keywords

Interaction

Subunit

The cytochrome bc1 complex contains 11 subunits: 3 respiratory subunits (MT-CYB, CYC1 and UQCRFS1), 2 core proteins (UQCRC1 and UQCRC2) and 6 low-molecular weight proteins (UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and a cleavage product of UQCRFS1). This cytochrome bc1 complex then forms a dimer.

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-209Cytochrome b/b6 N-terminal region profile
Domain210-379Cytochrome b/b6 C-terminal region profile

Sequence similarities

Belongs to the cytochrome b family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    379
  • Mass (Da)
    42,677
  • Last updated
    2007-10-23 v1
  • Checksum
    62D496197BBA8711
MTNIRKTHPLTKIINNSFIDLPAPSNISAWWNFGSLLGICLIIQILTGLFLAMHYTSDTATAFSSVTHICRDVNYGWIIRYMHANGASMFFICLFLHVGRGLYYGSYMFSETWNIGIILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIISALAAVHLLFLHETGSNNPSGIPSDSDKIPFHPYYTIKDILGALFLILTLMLLVLFSPDLLGDPDNYIPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVFSILVLAIIPLLHTSKQRSMMFRPLSQCLFWLLVADLLTLTWIGGQPVEHPFVTIGQLASILYFMILLVLMPIISIIENNMLKW

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
EF689080
EMBL· GenBank· DDBJ
ABU93741.1
EMBL· GenBank· DDBJ
Genomic DNA
EF689081
EMBL· GenBank· DDBJ
ABU93742.1
EMBL· GenBank· DDBJ
Genomic DNA
EF987744
EMBL· GenBank· DDBJ
ABV57065.1
EMBL· GenBank· DDBJ
Genomic DNA
GQ153573
EMBL· GenBank· DDBJ
ACT53025.1
EMBL· GenBank· DDBJ
Genomic DNA
HM106319
EMBL· GenBank· DDBJ
ADG22650.1
EMBL· GenBank· DDBJ
Genomic DNA
JN819537
EMBL· GenBank· DDBJ
AFH54005.1
EMBL· GenBank· DDBJ
Genomic DNA
JN819538
EMBL· GenBank· DDBJ
AFH54006.1
EMBL· GenBank· DDBJ
Genomic DNA
JN819539
EMBL· GenBank· DDBJ
AFH54007.1
EMBL· GenBank· DDBJ
Genomic DNA
JN819540
EMBL· GenBank· DDBJ
AFH54008.1
EMBL· GenBank· DDBJ
Genomic DNA
JN819549
EMBL· GenBank· DDBJ
AFH54017.1
EMBL· GenBank· DDBJ
Genomic DNA
JN819550
EMBL· GenBank· DDBJ
AFH54018.1
EMBL· GenBank· DDBJ
Genomic DNA
JN819551
EMBL· GenBank· DDBJ
AFH54019.1
EMBL· GenBank· DDBJ
Genomic DNA
JN819552
EMBL· GenBank· DDBJ
AFH54020.1
EMBL· GenBank· DDBJ
Genomic DNA
KT901457
EMBL· GenBank· DDBJ
ALT55499.1
EMBL· GenBank· DDBJ
Genomic DNA
KT693382
EMBL· GenBank· DDBJ
AMM05292.1
EMBL· GenBank· DDBJ
Genomic DNA
MF459691
EMBL· GenBank· DDBJ
AXJ93325.1
EMBL· GenBank· DDBJ
Genomic DNA
AB564122
EMBL· GenBank· DDBJ
BAK19348.1
EMBL· GenBank· DDBJ
Genomic DNA
AB564123
EMBL· GenBank· DDBJ
BAK19349.1
EMBL· GenBank· DDBJ
Genomic DNA
AB564125
EMBL· GenBank· DDBJ
BAK19351.1
EMBL· GenBank· DDBJ
Genomic DNA
AB564127
EMBL· GenBank· DDBJ
BAK19353.1
EMBL· GenBank· DDBJ
Genomic DNA
AB564128
EMBL· GenBank· DDBJ
BAK19354.1
EMBL· GenBank· DDBJ
Genomic DNA
AB564129
EMBL· GenBank· DDBJ
BAK19355.1
EMBL· GenBank· DDBJ
Genomic DNA
AB564130
EMBL· GenBank· DDBJ
BAK19356.1
EMBL· GenBank· DDBJ
Genomic DNA
LC324904
EMBL· GenBank· DDBJ
BBF88154.1
EMBL· GenBank· DDBJ
Genomic DNA
LC324905
EMBL· GenBank· DDBJ
BBF88155.1
EMBL· GenBank· DDBJ
Genomic DNA
LC324906
EMBL· GenBank· DDBJ
BBF88156.1
EMBL· GenBank· DDBJ
Genomic DNA
LC324907
EMBL· GenBank· DDBJ
BBF88157.1
EMBL· GenBank· DDBJ
Genomic DNA
LC324908
EMBL· GenBank· DDBJ
BBF88158.1
EMBL· GenBank· DDBJ
Genomic DNA
LC324909
EMBL· GenBank· DDBJ
BBF88159.1
EMBL· GenBank· DDBJ
Genomic DNA
LC324911
EMBL· GenBank· DDBJ
BBF88161.1
EMBL· GenBank· DDBJ
Genomic DNA
LC324913
EMBL· GenBank· DDBJ
BBF88163.1
EMBL· GenBank· DDBJ
Genomic DNA
LC324915
EMBL· GenBank· DDBJ
BBF88165.1
EMBL· GenBank· DDBJ
Genomic DNA
LC324916
EMBL· GenBank· DDBJ
BBF88166.1
EMBL· GenBank· DDBJ
Genomic DNA
LC324917
EMBL· GenBank· DDBJ
BBF88167.1
EMBL· GenBank· DDBJ
Genomic DNA
LC324918
EMBL· GenBank· DDBJ
BBF88168.1
EMBL· GenBank· DDBJ
Genomic DNA
LC324919
EMBL· GenBank· DDBJ
BBF88169.1
EMBL· GenBank· DDBJ
Genomic DNA
LC324920
EMBL· GenBank· DDBJ
BBF88170.1
EMBL· GenBank· DDBJ
Genomic DNA
LC324921
EMBL· GenBank· DDBJ
BBF88171.1
EMBL· GenBank· DDBJ
Genomic DNA
LC324923
EMBL· GenBank· DDBJ
BBF88173.1
EMBL· GenBank· DDBJ
Genomic DNA
LC324924
EMBL· GenBank· DDBJ
BBF88174.1
EMBL· GenBank· DDBJ
Genomic DNA
LC324925
EMBL· GenBank· DDBJ
BBF88175.1
EMBL· GenBank· DDBJ
Genomic DNA
LC324926
EMBL· GenBank· DDBJ
BBF88176.1
EMBL· GenBank· DDBJ
Genomic DNA
LC324927
EMBL· GenBank· DDBJ
BBF88177.1
EMBL· GenBank· DDBJ
Genomic DNA
LC324928
EMBL· GenBank· DDBJ
BBF88178.1
EMBL· GenBank· DDBJ
Genomic DNA
LC324929
EMBL· GenBank· DDBJ
BBF88179.1
EMBL· GenBank· DDBJ
Genomic DNA
LC324930
EMBL· GenBank· DDBJ
BBF88180.1
EMBL· GenBank· DDBJ
Genomic DNA
LC324933
EMBL· GenBank· DDBJ
BBF88183.1
EMBL· GenBank· DDBJ
Genomic DNA
LC324934
EMBL· GenBank· DDBJ
BBF88184.1
EMBL· GenBank· DDBJ
Genomic DNA
LC324936
EMBL· GenBank· DDBJ
BBF88186.1
EMBL· GenBank· DDBJ
Genomic DNA
LC324949
EMBL· GenBank· DDBJ
BBF88199.1
EMBL· GenBank· DDBJ
Genomic DNA
LC324952
EMBL· GenBank· DDBJ
BBF88202.1
EMBL· GenBank· DDBJ
Genomic DNA
AM258837
EMBL· GenBank· DDBJ
CAJ88860.1
EMBL· GenBank· DDBJ
Genomic DNA
AM258838
EMBL· GenBank· DDBJ
CAJ88861.1
EMBL· GenBank· DDBJ
Genomic DNA
AM258839
EMBL· GenBank· DDBJ
CAJ88862.1
EMBL· GenBank· DDBJ
Genomic DNA
AM258843
EMBL· GenBank· DDBJ
CAJ88866.1
EMBL· GenBank· DDBJ
Genomic DNA
AM258844
EMBL· GenBank· DDBJ
CAJ88867.1
EMBL· GenBank· DDBJ
Genomic DNA
AM258845
EMBL· GenBank· DDBJ
CAJ88868.1
EMBL· GenBank· DDBJ
Genomic DNA
AM258847
EMBL· GenBank· DDBJ
CAJ88870.1
EMBL· GenBank· DDBJ
Genomic DNA
AM258848
EMBL· GenBank· DDBJ
CAJ88871.1
EMBL· GenBank· DDBJ
Genomic DNA
AM258849
EMBL· GenBank· DDBJ
CAJ88872.1
EMBL· GenBank· DDBJ
Genomic DNA
AM258854
EMBL· GenBank· DDBJ
CAJ88877.1
EMBL· GenBank· DDBJ
Genomic DNA
AM258861
EMBL· GenBank· DDBJ
CAJ88884.1
EMBL· GenBank· DDBJ
Genomic DNA
AM258862
EMBL· GenBank· DDBJ
CAJ88885.1
EMBL· GenBank· DDBJ
Genomic DNA
AM258864
EMBL· GenBank· DDBJ
CAJ88887.1
EMBL· GenBank· DDBJ
Genomic DNA
AM258865
EMBL· GenBank· DDBJ
CAJ88888.1
EMBL· GenBank· DDBJ
Genomic DNA
AM258869
EMBL· GenBank· DDBJ
CAJ88892.1
EMBL· GenBank· DDBJ
Genomic DNA
AM258871
EMBL· GenBank· DDBJ
CAJ88894.1
EMBL· GenBank· DDBJ
Genomic DNA
AM258872
EMBL· GenBank· DDBJ
CAJ88895.1
EMBL· GenBank· DDBJ
Genomic DNA
AM258873
EMBL· GenBank· DDBJ
CAJ88896.1
EMBL· GenBank· DDBJ
Genomic DNA
AM258874
EMBL· GenBank· DDBJ
CAJ88897.1
EMBL· GenBank· DDBJ
Genomic DNA
AM258875
EMBL· GenBank· DDBJ
CAJ88898.1
EMBL· GenBank· DDBJ
Genomic DNA
AM258876
EMBL· GenBank· DDBJ
CAJ88899.1
EMBL· GenBank· DDBJ
Genomic DNA
AM258877
EMBL· GenBank· DDBJ
CAJ88900.1
EMBL· GenBank· DDBJ
Genomic DNA
AM258878
EMBL· GenBank· DDBJ
CAJ88901.1
EMBL· GenBank· DDBJ
Genomic DNA
AM258879
EMBL· GenBank· DDBJ
CAJ88902.1
EMBL· GenBank· DDBJ
Genomic DNA
AM258880
EMBL· GenBank· DDBJ
CAJ88903.1
EMBL· GenBank· DDBJ
Genomic DNA
AM258882
EMBL· GenBank· DDBJ
CAJ88905.1
EMBL· GenBank· DDBJ
Genomic DNA
AM258887
EMBL· GenBank· DDBJ
CAJ88910.1
EMBL· GenBank· DDBJ
Genomic DNA
AM258889
EMBL· GenBank· DDBJ
CAJ88912.1
EMBL· GenBank· DDBJ
Genomic DNA
AM258890
EMBL· GenBank· DDBJ
CAJ88913.1
EMBL· GenBank· DDBJ
Genomic DNA
AM258891
EMBL· GenBank· DDBJ
CAJ88914.1
EMBL· GenBank· DDBJ
Genomic DNA
AM932884
EMBL· GenBank· DDBJ
CAP69673.1
EMBL· GenBank· DDBJ
Genomic DNA
AM932885
EMBL· GenBank· DDBJ
CAP69674.1
EMBL· GenBank· DDBJ
Genomic DNA
MW257229
EMBL· GenBank· DDBJ
QQW47906.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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