A7YDD5 · A7YDD5_ICHUN

Function

function

Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentmitochondrial inner membrane
Cellular Componentproton-transporting ATP synthase complex, coupling factor F(o)
Molecular Functionproton-transporting ATP synthase activity, rotational mechanism

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    ATP synthase subunit a

Gene names

    • Name
      ATPase6

Encoded on

  • Mitochondrion

Organism names

Accessions

  • Primary accession
    A7YDD5

Subcellular Location

Membrane
; Multi-pass membrane protein
Mitochondrion inner membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane12-32Helical
Transmembrane69-93Helical
Transmembrane129-152Helical
Transmembrane172-197Helical
Transmembrane204-222Helical

Keywords

Family & Domains

Sequence similarities

Belongs to the ATPase A chain family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    237
  • Mass (Da)
    26,332
  • Last updated
    2007-10-23 v1
  • Checksum
    0C94C073E96E62F3
MTLDIFDQFISPTILGLPLAWLAMLVPSLMLITQTPKFIKSRYHTLLNPILTTITKQLFISMSPQGHKWALMCMASMMFILVINLLGLLPYTYTPTTQLSLNMGLAVPLWLATIIIGMQKKPTEALAHLLPEGTPIALIPMLIIIETISLFIRPVALGVRLTANLTAGHLLMQLISITTFMLIPIISISMITSLLLLLLTILELAVAMIQAYVFILLLTLYLQENIYVPPSSRMPHG

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
DQ889794
EMBL· GenBank· DDBJ
ABK19999.1
EMBL· GenBank· DDBJ
Genomic DNA
DQ889795
EMBL· GenBank· DDBJ
ABK20001.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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