A7UAK5 · A7UAK5_MOUSE

  • Protein
    6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 3 splice variant 2
  • Gene
    Pfkfb3
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    3/5

Function

Features

Showing features for binding site, active site.

155550100150200250300350400450500550
TypeIDPosition(s)Description
Binding site253-260substrate
Active site254Tele-phosphohistidine intermediate
Active site323Proton donor/acceptor

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentnucleoplasm
Molecular Function6-phosphofructo-2-kinase activity
Molecular FunctionATP binding
Molecular Functionfructose-2,6-bisphosphate 2-phosphatase activity
Biological Processapoptotic process
Biological Processfructose 2,6-bisphosphate metabolic process
Biological Processfructose metabolic process
Biological Processglial cell differentiation
Biological Processglycolytic process
Biological Processmotor behavior

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Submitted names
    • 6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 3 splice variant 2
      (EC:2.7.1.105
      , EC:3.1.3.46
      )
    • 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3

Gene names

    • Name
      Pfkfb3

Organism names

  • Taxonomic identifier
  • Organism
  • Strains
    • C57BL/6
    • C57BL/6J
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus

Accessions

  • Primary accession
    A7UAK5

Proteomes

Organism-specific databases

Subcellular Location

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, region.

TypeIDPosition(s)Description
Domain26-2466-phosphofructo-2-kinase
Region474-504Disordered

Sequence similarities

In the C-terminal section; belongs to the phosphoglycerate mutase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    555
  • Mass (Da)
    63,653
  • Last updated
    2007-10-02 v1
  • Checksum
    89E9DFC05B01E508
MPLELTQSRVQKIWVPVDHRPSLPRSCGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLNWIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMRVRKQCALAALRDVKSYLTKEGGQIAVFDATNTTRERRHMILNFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCNSAEAMDDFMKRINCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLMNIHVQPRTIYLCRHGENEYNLQGKIGGDSGLSSRGKKFANALSKFVEEQNLKDLRVWTSQLKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTGESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKLTPVAYGCRVESIYLNVESVSTHRERSEAVKIQHFASVVRPSSYTELDFQSVESAKQDAKKGPNPLMRRNSVTPLASPEPTKKPRINSFEERVASTSAALPSCLPPEVPTQLPGQPLLGKACLRSVCHIFSKFSPY

Computationally mapped potential isoform sequences

There are 10 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A2AUP5A2AUP5_MOUSEPfkfb3514
A2AUP3A2AUP3_MOUSEPfkfb3513
A2AUP4A2AUP4_MOUSEPfkfb3542
A2AUP1A2AUP1_MOUSEPfkfb3520
Q3U3S6Q3U3S6_MOUSEPfkfb3549
A0A0A6YW89A0A0A6YW89_MOUSEPfkfb3327
A0A0A6YY64A0A0A6YY64_MOUSEPfkfb3500
Q7TS91Q7TS91_MOUSEPfkfb3526
A7UAK4A7UAK4_MOUSEPfkfb3462
A7UAK8A7UAK8_MOUSEPfkfb3543

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
EU034676
EMBL· GenBank· DDBJ
ABS88613.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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