A7MJ61 · PIMT_CROS8
- ProteinProtein-L-isoaspartate O-methyltransferase
- Genepcm
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids208 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
Catalytic activity
- [protein]-L-isoaspartate + S-adenosyl-L-methionine = [protein]-L-isoaspartate alpha-methyl ester + S-adenosyl-L-homocysteine
Features
Showing features for active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 59 | ||||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | protein-L-isoaspartate (D-aspartate) O-methyltransferase activity | |
Biological Process | methylation | |
Biological Process | protein modification process | |
Biological Process | protein repair |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameProtein-L-isoaspartate O-methyltransferase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Cronobacter
Accessions
- Primary accessionA7MJ61
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_1000004818 | 1-208 | Protein-L-isoaspartate O-methyltransferase | ||
Structure
Sequence
- Sequence statusComplete
- Length208
- Mass (Da)23,286
- Last updated2007-10-02 v1
- Checksum3D111EBE471F6A7E
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP000783 EMBL· GenBank· DDBJ | ABU75839.1 EMBL· GenBank· DDBJ | Genomic DNA |