A7EVV6 · PTF_SCLS1

Function

function

Prenyltransferase that attaches isoprenoid moieties to carbon atoms of aromatic substrates in an enzyme-catalyzed Friedel-Crafts reaction (PubMed:20351110).
Shows specificity for dimethylallyl diphosphate (DMAPP) and does not accept geranyl diphosphate (GPP) or isopentenyl diphosphate (IPP) (PubMed:20351110).
Prenylates the artificial substrate 2,7-dihydroxynaphthalene (2,7-DHN), as well as dihydrophenazine-1-carboxylic acid and 4-hydroxybenzoic acid at lower levels (PubMed:20351110).
Only traces of products are detected with aspulvinone E or flaviolin as substrates; and no product is formed with L-tryptophan, L-tyrosine, or 4-hydroxyphenylpyruvate (PubMed:20351110).
Ptf seems no to be involved in the prenylation reaction in the biosynthesis of aspulvinone H and J and the physiological function of ptf remains unknown (PubMed:20351110).

Miscellaneous

The gene is not located within a recognizable secondary metabolic gene cluster.

Kinetics

KM SUBSTRATE pH TEMPERATURE[C] NOTES EVIDENCE
1232 μMDMAPP
590 μM2,7-dihydroxynaphthalene

GO annotations

AspectTerm
Molecular Functionprenyltransferase activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Aromatic prenyltransferase
  • EC number

Gene names

    • Name
      ptf
    • ORF names
      SS1G_09465

Organism names

Accessions

  • Primary accession
    A7EVV6
  • Secondary accessions
    • A0A1D9QLA6

Proteomes

Organism-specific databases

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004554631-309Aromatic prenyltransferase

Structure

Family & Domains

Sequence similarities

Belongs to the aromatic prenyltransferase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    309
  • Mass (Da)
    34,721
  • Last updated
    2007-09-11 v1
  • Checksum
    75E5439230B5AAD1
MVVQLISKPSKFSQSRFLDDIRNLSAAINAPYSERTTIEALSVYSHSFHNGVVLWRVTDRPGDALNYRFYSREPIDTVSIAASAGLLSPDIANTLGKLVTSWSSLYDGTPEESCDFDAEKGLVKAWVYFGGMRPLDDILGAEGVPESVRQHEKRFKELGLQKVRHVAVDYHKQTVNLYFRAQGPISFQQATAFNALAGAEPPSQSQFIEMREFLNAVGYTFAVTINIDSGDIERVGYYALKLPERSAKKWPAINAQLERFVQFAPSYDREEMNAVAWSFGERKTYVKFERSYCGELIPLIKGWGTTLSS

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CH476633
EMBL· GenBank· DDBJ
EDN93598.1
EMBL· GenBank· DDBJ
Genomic DNA
CP017828
EMBL· GenBank· DDBJ
APA15717.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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