A7EM78 · DBP9_SCLS1

Function

function

ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs.

Catalytic activity

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site68-75ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentnucleolus
Molecular FunctionATP binding
Molecular FunctionATP hydrolysis activity
Molecular FunctionRNA binding
Molecular FunctionRNA helicase activity
Biological ProcessrRNA processing

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    ATP-dependent RNA helicase dbp9
  • EC number

Gene names

    • Name
      dbp9
    • ORF names
      SS1G_06425

Organism names

Accessions

  • Primary accession
    A7EM78

Proteomes

Organism-specific databases

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00003102561-607ATP-dependent RNA helicase dbp9

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for motif, domain, region, compositional bias.

TypeIDPosition(s)Description
Motif24-52Q motif
Domain55-232Helicase ATP-binding
Motif180-183DEAD box
Domain243-475Helicase C-terminal
Region332-380Disordered
Compositional bias335-352Acidic residues
Compositional bias353-368Basic and acidic residues
Region580-607Disordered

Domain

The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    607
  • Mass (Da)
    67,588
  • Last updated
    2007-09-11 v1
  • Checksum
    490FC03B7F5F0E35
MKRKLDVNDVPVPTEEAEAANGKATFASLGLDARLLQGIAKQNFQSPTLVQSKAIPLTLEGRDILARAKTGSGKTAAYLLPILHSILKRKELSPTQCTSALILVPTRELADQVYKTVESFTAFCAKDVRAVNLTQRVSDAVQRSLLADSPDIVIATPARASLNANTSALLLTNLTHMVIDEADLVLSYGYDEDLQNVAKIMPKGVQTVLMSATLTSEVETLKGLFCRNPEVLKLEEAEDEGKGVSQFVVKCAEDEKFLLVYVIFKLKLIKGKCIIFVGDIDRCYRLKLFLEQFGTRSCILNSQLPVNSRIHVVEEFNKNVYDIIIASDEHEVLGDEDEPKPEETEEVEADDASGEKEDAKDAKKETKQPSKKKQKTGKKDKEYGVSRGIDFKNVACVLNFDLPTSSKSYTHRIGRTARAGQTGMALSFVIPSALYRKHKPTSIESAKDDEKVLAKIIKHQAKKGKEVKPYNFDMKQVDAFRYRMGDALRAVTSIAVQEAKAREIRQELMKSEKLKRHFEENPSDLYHLRHDGELRPARVQAHLKHVPDYLLPKEGKKGITGGDIGFVGMHKTTENRIRKARAANKAKGRGKGRKSDPLKTFKAKSRK

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias335-352Acidic residues
Compositional bias353-368Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CH476628
EMBL· GenBank· DDBJ
EDO03944.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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