A7EKT5 · MCR1_SCLS1
- ProteinNADH-cytochrome b5 reductase 2
- Genemcr1
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids345 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
May mediate the reduction of outer membrane cytochrome b5.
Catalytic activity
- 2 Fe(III)-[cytochrome b5] + NADH = 2 Fe(II)-[cytochrome b5] + NAD+ + H+
Cofactor
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 202-237 | FAD (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | mitochondrial outer membrane | |
Molecular Function | cytochrome-b5 reductase activity, acting on NAD(P)H | |
Biological Process | ergosterol biosynthetic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameNADH-cytochrome b5 reductase 2
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Leotiomycetes > Helotiales > Sclerotiniaceae > Sclerotinia
Accessions
- Primary accessionA7EKT5
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Mitochondrion outer membrane ; Single-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 31-47 | Helical | |||
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000330190 | 1-345 | NADH-cytochrome b5 reductase 2 | ||
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 94-199 | FAD-binding FR-type | |||
Sequence similarities
Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length345
- Mass (Da)37,819
- Last updated2007-09-11 v1
- Checksum802B93D76510FC22
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CH476627 EMBL· GenBank· DDBJ | EDO03451.1 EMBL· GenBank· DDBJ | Genomic DNA |