A7AS20 · A7AS20_BABBO

  • Protein
    Phosphomannomutase
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Pathway

Nucleotide-sugar biosynthesis; GDP-alpha-D-mannose biosynthesis; alpha-D-mannose 1-phosphate from D-fructose 6-phosphate: step 2/2.

Features

Showing features for active site, binding site.

Type
IDPosition(s)Description
Active site9Nucleophile
Binding site9Mg2+ 1 (UniProtKB | ChEBI)
Active site11Proton donor/acceptor
Binding site11Mg2+ 1 (UniProtKB | ChEBI)
Binding site121alpha-D-mannose 1-phosphate (UniProtKB | ChEBI)
Binding site132alpha-D-mannose 1-phosphate (UniProtKB | ChEBI)
Binding site139alpha-D-mannose 1-phosphate (UniProtKB | ChEBI)
Binding site179alpha-D-mannose 1-phosphate (UniProtKB | ChEBI)
Binding site181alpha-D-mannose 1-phosphate (UniProtKB | ChEBI)
Binding site207Mg2+ 1 (UniProtKB | ChEBI)
Binding site219Mg2+ 1 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionmetal ion binding
Molecular Functionphosphomannomutase activity
Biological ProcessGDP-mannose biosynthetic process
Biological Processmannose metabolic process
Biological Processprotein N-linked glycosylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phosphomannomutase
  • EC number

Gene names

    • ORF names
      BBOV_IV009850

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • T2Bo
  • Taxonomic lineage
    Eukaryota > Sar > Alveolata > Apicomplexa > Aconoidasida > Piroplasmida > Babesiidae > Babesia

Accessions

  • Primary accession
    A7AS20

Proteomes

Organism-specific databases

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the eukaryotic PMM family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    246
  • Mass (Da)
    28,186
  • Last updated
    2007-09-11 v1
  • Checksum
    92E294A817B36CFF
MVRQMLIFDMDGTLTDPVQVISNNVKDILRRCKLKNFEIAVVSGSKYDKIKGQLNDGFIDEFDYVFSENGTQVYVKNVLVKSLDITEAIPETKLRKMIEFSLRYIADLDIPTKRGTFIEHRKSLINICPPGRNSSMDDRRRFVEYDSIHHVRQKFIQVLKSQFDSDDCPLSFVAGGQISIDVYPKAWSKSIALSHIEKCDVIHFFGDNTREGGNDFEIYNHPDVIGHTVTGYKDLVNQLEELLAKS

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AAXT01000002
EMBL· GenBank· DDBJ
EDO07339.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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