A7AS20 · A7AS20_BABBO
- ProteinPhosphomannomutase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids246 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.
Catalytic activity
- alpha-D-mannose 1-phosphate = D-mannose 6-phosphate
Cofactor
Pathway
Nucleotide-sugar biosynthesis; GDP-alpha-D-mannose biosynthesis; alpha-D-mannose 1-phosphate from D-fructose 6-phosphate: step 2/2.
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 9 | Nucleophile | |||
Binding site | 9 | Mg2+ 1 (UniProtKB | ChEBI) | |||
Active site | 11 | Proton donor/acceptor | |||
Binding site | 11 | Mg2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 121 | alpha-D-mannose 1-phosphate (UniProtKB | ChEBI) | |||
Binding site | 132 | alpha-D-mannose 1-phosphate (UniProtKB | ChEBI) | |||
Binding site | 139 | alpha-D-mannose 1-phosphate (UniProtKB | ChEBI) | |||
Binding site | 179 | alpha-D-mannose 1-phosphate (UniProtKB | ChEBI) | |||
Binding site | 181 | alpha-D-mannose 1-phosphate (UniProtKB | ChEBI) | |||
Binding site | 207 | Mg2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 219 | Mg2+ 1 (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | metal ion binding | |
Molecular Function | phosphomannomutase activity | |
Biological Process | GDP-mannose biosynthetic process | |
Biological Process | mannose metabolic process | |
Biological Process | protein N-linked glycosylation |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePhosphomannomutase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Sar > Alveolata > Apicomplexa > Aconoidasida > Piroplasmida > Babesiidae > Babesia
Accessions
- Primary accessionA7AS20
Proteomes
Organism-specific databases
Subcellular Location
Interaction
Structure
Sequence
- Sequence statusComplete
- Length246
- Mass (Da)28,186
- Last updated2007-09-11 v1
- Checksum92E294A817B36CFF
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AAXT01000002 EMBL· GenBank· DDBJ | EDO07339.1 EMBL· GenBank· DDBJ | Genomic DNA |