A6WQP0 · GUAA_SHEB8

Function

function

Catalyzes the synthesis of GMP from XMP.

Catalytic activity

Pathway

Purine metabolism; GMP biosynthesis; GMP from XMP (L-Gln route): step 1/1.

Features

Showing features for active site, binding site.

152550100150200250300350400450500
Type
IDPosition(s)Description
Active site85Nucleophile
Active site181
Active site183
Binding site235-241ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular FunctionATP binding
Molecular FunctionGMP synthase activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    GMP synthase [glutamine-hydrolyzing]
  • EC number
  • Alternative names
    • GMP synthetase
    • Glutamine amidotransferase

Gene names

    • Name
      guaA
    • Ordered locus names
      Shew185_2998

Organism names

Accessions

  • Primary accession
    A6WQP0

Subcellular Location

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_10001203991-525GMP synthase [glutamine-hydrolyzing]

Interaction

Subunit

Homodimer.

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain8-207Glutamine amidotransferase type-1
Domain208-400GMPS ATP-PPase

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    525
  • Mass (Da)
    58,224
  • Last updated
    2007-08-21 v1
  • MD5 Checksum
    7C8447392FEF51C9F3AD4C2DD8D9B7B5
MSDIHEHKILILDFGSQYTQLIARRIREIGVYCELWAWDVTEAQIREFAPNGIILAGGPESVTAENSPRAPEYVFTAGVPVLGICYGMQTMSEQLGGKVIQGVGEGEFGYAQIEMLTDSLLFKGIEDAVNSEGKPLLDVWMSHGDKVSAIPEGFVAVAKTDTCPFAAMANEEKQFFGVQFHPEVTHTRQGMRMLSHFALDICGCAANWKPSSIIEDAIERLKKQIGDDEVILGLSGGVDSSVVAMLLHRAIGKKLTCVFVDNGLLRLNEAEQVMEMFGDHFGLNIIHVDAENRFLDAMKGEADPEAKRKIIGRVFVEIFDEESKKCANAKWLAQGTIYPDVIESAGSATGKAHVIKSHHNVGGLPDDMELGLVEPLRELFKDEVRKIGLELGLPYNMLYRHPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELHKADLYNKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETVDFMTAHWAHLPYDFLGRVSNRIINEVDGISRVVYDISGKPPATIEWE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000753
EMBL· GenBank· DDBJ
ABS09129.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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