A6TFQ6 · A6TFQ6_KLEP7

Function

function

Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

Catalytic activity

Pathway

Carbohydrate biosynthesis; gluconeogenesis.
Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate from glycerone phosphate: step 1/1.
Carbohydrate metabolism; erythritol degradation.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site3-5substrate
Active site89Electrophile
Active site161Proton acceptor
Binding site167substrate
Binding site206substrate
Binding site227-228substrate

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functiontriose-phosphate isomerase activity
Biological Processgluconeogenesis
Biological Processglyceraldehyde-3-phosphate biosynthetic process
Biological Processglycerol catabolic process
Biological Processglycolytic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Triosephosphate isomerase
  • EC number
  • Short names
    TIM
    ; TPI
  • Alternative names
    • Triose-phosphate isomerase

Gene names

    • Name
      tpiA
    • ORF names
      KPN_04005

Organism names

Accessions

  • Primary accession
    A6TFQ6

Proteomes

Subcellular Location

Keywords

PTM/Processing

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the triosephosphate isomerase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    249
  • Mass (Da)
    26,176
  • Last updated
    2007-08-21 v1
  • Checksum
    C724DEDEE7EBA911
MGNWKLNGSRHMVNELVANLRTELAGVSGCAVAIAPPEMYLDLAKRAAEGSHIHLGAQNVDVNLSGAFTGETSAEMLKDIGAQYIIIGHSERRTYHKESDELIAKKFAVLKEQGLTPVLCIGETEAENEAGKTEEVCARQIDAVLKTQGAAAFEGVVIAYEPVWAIGTGKSATPAQAQAVHKFIRDHIAKADAKIAEQVIIQYGGSVNAGNAAELFTQPDIDGALVGGASLKADAFAVIVKAAEAAKKA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000647
EMBL· GenBank· DDBJ
ABR79390.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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