A6T7U7 · CHBG_KLEP7
- ProteinChitooligosaccharide deacetylase
- GenechbG
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids252 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score4/5
Function
function
Involved in the degradation of chitin. ChbG is essential for growth on the acetylated chitooligosaccharides chitobiose and chitotriose but is dispensable for growth on cellobiose and chitosan dimer, the deacetylated form of chitobiose. Deacetylation of chitobiose-6-P and chitotriose-6-P is necessary for both the activation of the chb promoter by the regulatory protein ChbR and the hydrolysis of phosphorylated beta-glucosides by the phospho-beta-glucosidase ChbF. Catalyzes the removal of only one acetyl group from chitobiose-6-P to yield monoacetylchitobiose-6-P, the inducer of ChbR and the substrate of ChbF.
Catalytic activity
- H2O + N,N'-diacetylchitobiose = acetate + N-acetyl-beta-D-glucosaminyl-(1->4)-D-glucosamine
- diacetylchitobiose-6'-phosphate + H2O = acetate + N'-monoacetylchitobiose-6'-phosphate
Cofactor
Pathway
Glycan degradation; chitin degradation.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | chitin disaccharide deacetylase activity | |
Molecular Function | deacetylase activity | |
Molecular Function | metal ion binding | |
Biological Process | chitin catabolic process | |
Biological Process | diacetylchitobiose catabolic process | |
Biological Process | polysaccharide catabolic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameChitooligosaccharide deacetylase
- EC number
- Short namesCOD
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Klebsiella/Raoultella group > Klebsiella
Accessions
- Primary accessionA6T7U7
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_1000067084 | 1-252 | Chitooligosaccharide deacetylase | |||
Sequence: MERVLIVNADDFGLSKGQNYGIIEACRNGVVTSTTALVNGAAIDHAAQLGRSTPELAVGMHFVLTLGEPLSAMPGLTRDGRLGKWIWQQAEEDSLPLEEIAHELACQYHRFVELFGHEPTHIDSHHHVHMFAQIYPIVAAFAREKGIALRIDRQVAAQSGLDQQAARSSAGFSSEFYGEAVSEELFLQTLDASIARGERSLEVMCHPAYVDRIIMGSAYCYPRLDELDVLTAASLKAAVADRGYRLGTYRDV |
Proteomic databases
Interaction
Structure
Sequence
- Sequence statusComplete
- Length252
- Mass (Da)27,685
- Last updated2007-08-21 v1
- Checksum3E728EE248274549
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP000647 EMBL· GenBank· DDBJ | ABR76668.1 EMBL· GenBank· DDBJ | Genomic DNA |