A6T7U7 · CHBG_KLEP7

Function

function

Involved in the degradation of chitin. ChbG is essential for growth on the acetylated chitooligosaccharides chitobiose and chitotriose but is dispensable for growth on cellobiose and chitosan dimer, the deacetylated form of chitobiose. Deacetylation of chitobiose-6-P and chitotriose-6-P is necessary for both the activation of the chb promoter by the regulatory protein ChbR and the hydrolysis of phosphorylated beta-glucosides by the phospho-beta-glucosidase ChbF. Catalyzes the removal of only one acetyl group from chitobiose-6-P to yield monoacetylchitobiose-6-P, the inducer of ChbR and the substrate of ChbF.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Pathway

Glycan degradation; chitin degradation.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site61Mg2+ (UniProtKB | ChEBI)
Binding site125Mg2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionchitin disaccharide deacetylase activity
Molecular Functiondeacetylase activity
Molecular Functionmetal ion binding
Biological Processchitin catabolic process
Biological Processdiacetylchitobiose catabolic process
Biological Processpolysaccharide catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Chitooligosaccharide deacetylase
  • EC number
  • Short names
    COD
  • Alternative names
    • Chitin disaccharide deacetylase
    • Chitobiose deacetylase
    • Chitobiose-6P deacetylase
    • Chitotriose deacetylase
    • Chitotriose-6P deacetylase

Gene names

    • Name
      chbG
    • ORF names
      KPN_01235
    • Ordered locus names
      KPN78578_12070

Organism names

Accessions

  • Primary accession
    A6T7U7

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_10000670841-252Chitooligosaccharide deacetylase

Proteomic databases

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the YdjC deacetylase family. ChbG subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    252
  • Mass (Da)
    27,685
  • Last updated
    2007-08-21 v1
  • Checksum
    3E728EE248274549
MERVLIVNADDFGLSKGQNYGIIEACRNGVVTSTTALVNGAAIDHAAQLGRSTPELAVGMHFVLTLGEPLSAMPGLTRDGRLGKWIWQQAEEDSLPLEEIAHELACQYHRFVELFGHEPTHIDSHHHVHMFAQIYPIVAAFAREKGIALRIDRQVAAQSGLDQQAARSSAGFSSEFYGEAVSEELFLQTLDASIARGERSLEVMCHPAYVDRIIMGSAYCYPRLDELDVLTAASLKAAVADRGYRLGTYRDV

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000647
EMBL· GenBank· DDBJ
ABR76668.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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