A6RBI0 · DAPB_AJECN
- ProteinProbable dipeptidyl-aminopeptidase B
- GeneDAPB
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids922 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Type IV dipeptidyl-peptidase which removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.
Catalytic activity
Features
Showing features for active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 756 | Charge relay system | |||
Active site | 833 | Charge relay system | |||
Active site | 866 | Charge relay system | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Cellular Component | vacuolar membrane | |
Molecular Function | aminopeptidase activity | |
Molecular Function | dipeptidyl-peptidase activity | |
Molecular Function | serine-type peptidase activity | |
Biological Process | proteolysis |
Keywords
- Molecular function
Enzyme and pathway databases
Protein family/group databases
Names & Taxonomy
Protein names
- Recommended nameProbable dipeptidyl-aminopeptidase B
- EC number
- Short namesDPAP B
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Eurotiomycetes > Eurotiomycetidae > Onygenales > Ajellomycetaceae > Histoplasma
Accessions
- Primary accessionA6RBI0
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Vacuole membrane ; Single-pass type II membrane protein
Note: Lysosome-like vacuoles.
Features
Showing features for topological domain, transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Topological domain | 1-99 | Cytoplasmic | |||
Transmembrane | 100-120 | Helical; Signal-anchor for type II membrane protein | |||
Topological domain | 121-922 | Vacuolar | |||
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain, glycosylation.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000412126 | 1-922 | Probable dipeptidyl-aminopeptidase B | ||
Glycosylation | 135 | N-linked (GlcNAc...) asparagine | |||
Glycosylation | 200 | N-linked (GlcNAc...) asparagine | |||
Glycosylation | 351 | N-linked (GlcNAc...) asparagine | |||
Glycosylation | 574 | N-linked (GlcNAc...) asparagine | |||
Glycosylation | 815 | N-linked (GlcNAc...) asparagine | |||
Glycosylation | 902 | N-linked (GlcNAc...) asparagine | |||
Keywords
- PTM
PTM databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for compositional bias, region.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 1-19 | Basic and acidic residues | |||
Region | 1-21 | Disordered | |||
Sequence similarities
Belongs to the peptidase S9B family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length922
- Mass (Da)104,147
- Last updated2007-08-21 v1
- Checksum34932E3C1D124CDE
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 1-19 | Basic and acidic residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CH476661 EMBL· GenBank· DDBJ | EDN10515.1 EMBL· GenBank· DDBJ | Genomic DNA |