A6Q0G4 · A6Q0G4_MESCR
- ProteinSodium/hydrogen exchanger
- Genenhx2
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids526 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score2/5
Function
Catalytic activity
- H+(out) + K+(in) = H+(in) + K+(out)
- H+(out) + Na+(in) = H+(in) + Na+(out)
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | membrane | |
Molecular Function | sodium:proton antiporter activity | |
Biological Process | potassium ion transport | |
Biological Process | regulation of pH |
Keywords
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameSodium/hydrogen exchanger
Gene names
Organism names
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > Caryophyllales > Aizoaceae > Mesembryanthemum > Mesembryanthemum subgen. Cryophytum
Accessions
- Primary accessionA6Q0G4
Subcellular Location
UniProt Annotation
GO Annotation
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 21-43 | Helical | ||||
Sequence: AAGVGILLQIMMLVLSFILGHVL | ||||||
Transmembrane | 49-67 | Helical | ||||
Sequence: FYIPEVSASLLIGLVVGGL | ||||||
Transmembrane | 87-104 | Helical | ||||
Sequence: FFFLFLLPPIIFQSGFIL | ||||||
Transmembrane | 116-137 | Helical | ||||
Sequence: IVTFSILGTFIASVLTGLLVYL | ||||||
Transmembrane | 220-247 | Helical | ||||
Sequence: VGFLETFVGSLSSGVGVGFIPALLFKYA | ||||||
Transmembrane | 267-290 | Helical | ||||
Sequence: YFSYMLAEGLGLSGIVSILFTGIV | ||||||
Transmembrane | 310-328 | Helical | ||||
Sequence: FFHLISSLAETFIFIYMGL | ||||||
Transmembrane | 340-365 | Helical | ||||
Sequence: VGFIFFSIIFIVISRAVNVFSCGYLI | ||||||
Transmembrane | 386-402 | Helical | ||||
Sequence: SGLRGAMAFALALQSVH | ||||||
Transmembrane | 408-428 | Helical | ||||
Sequence: HSQTIFTATTAIVVLTVLLIG |
Keywords
- Cellular component
Structure
Family & Domains
Features
Showing features for domain, region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 38-436 | Cation/H+ exchanger | ||||
Sequence: ILGHVLRRHKFFYIPEVSASLLIGLVVGGLANISNTETSIRGWFNFHEEFFFLFLLPPIIFQSGFILSPKPFFSNFGAIVTFSILGTFIASVLTGLLVYLGGITFLMYKLPLIECMMFGALISSTDPVTVLAIFQELGTDVNLYALVFGESVLNDAVAISLYRTMSLLNSHMSTGQNIFTLVVGFLETFVGSLSSGVGVGFIPALLFKYAGLDIDNLQNLESCLFVLFPYFSYMLAEGLGLSGIVSILFTGIVMKHYTFSNLSEKSQQFVSEFFHLISSLAETFIFIYMGLDIVMEKHSWSHVGFIFFSIIFIVISRAVNVFSCGYLINLARPAHRKIPMKHQKAPWYSGLRGAMAFALALQSVHDLPEGHSQTIFTATTAIVVLTVLLIGGSTGTMLE | ||||||
Region | 452-472 | Disordered | ||||
Sequence: GFNRSDGYVSPSQDEEESSSN | ||||||
Region | 501-526 | Disordered | ||||
Sequence: TTQSGDEEEHETLMPSPRREVYLSRN |
Sequence similarities
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length526
- Mass (Da)58,164
- Last updated2007-08-21 v1
- Checksum5E6AE27967C1FFA1