A6NE52 · WDR97_HUMAN
- ProteinWD repeat-containing protein 97
- GeneWDR97
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids1622 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameWD repeat-containing protein 97
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo
Accessions
- Primary accessionA6NE52
- Secondary accessions
Proteomes
Organism-specific databases
Disease & Variants
Features
Showing features for natural variant.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Natural variant | VAR_043029 | 149 | in dbSNP:rs4977196 | |||
Sequence: R → G | ||||||
Natural variant | VAR_043030 | 427 | in dbSNP:rs34324679 | |||
Sequence: H → Q | ||||||
Natural variant | VAR_043031 | 537 | in dbSNP:rs13250446 | |||
Sequence: E → G |
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 1,912 variants from UniProt as well as other sources including ClinVar and dbSNP.
Organism-specific databases
Miscellaneous
Genetic variation databases
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000332994 | 1-1622 | WD repeat-containing protein 97 | |||
Sequence: MEAEVWEAEGYNLVLDSDLYDADGYDVPDPGLLTEKNELTFTEPSQVLPFLTSSQQWQSLTPRARARRLWLLLRTSLHEVVEKEKRAELRAARLTHGLEPLRRLEVAAGLRSVAQDPVGGRFVVLDGAGRLHLHKEDGWAQETLLAPVRLTGLVTVLGPLGAVGRFVGWGPAGLAILRPNLSLLWLSEQGVGRAPGWAPTCCLPVPDLRLLLVAEMNSSLALWQFRSGGRRLVLRGSALHPPPSPTGRLMRLAVAPVPPHHVLRCFAAYGSAVLTFDLHAWTLVDVRRDLHKTTISDLAYCEEVEAMVTASRDSTVKVWEADWQIRMVFVGHTGPVTAMTVLPNTTLVLSASQDGTLRTWDLQAAAQVGEVALGFWGQDKLSRRVGRLLAPVRPGWPVLSLCASSMQLWRVRELYSPLAQLPAKVLHVQVAPALPAPAHQSLPTRLVCACADGSVYLLSAATGRIVSSLLLEPEDCAAAVAYCLPREALWLLTRAGHLVRANAARCPMSVLHRVCPPPPPAPQPCCLHLYSHLTDLEGAFSSWEIVRQHWGELRCSSVACAWKNKNRYLPVVGHTDGTLSVLEWLSSKTVFQTEAHSPGPVVAIASTWNSIVSSGGDLTVKMWRVFPYAEESLSLLRTFSCCYPAVALCALGRRVTAGFEDPDSATYGLVQFGLGDSPRLDHRPQDDPTDHITGLCCCPTLKLYACSSLDCTVRIWTAENRLLRLLQLNGAPQALAFCSNSGDLVLALGSRLCLVSHRLYLPTSYLVKKMCRKAPDVVDDPPLPLMSQESLTSAQLQRLTNLHGAASLSEALSLIHRRRATSQHLVPKEDLDAIVARDRDLQQLRLGLVVPAAQPPPSWQQRQEGFDNYLRLIYGSGLLGMQSGRGSQQWSAGTLRVERETRDVCAVPQAAHCLARAEVSTAAQTVPTALSPQDLGALGQHFSQSPRVTVPIPPTHRRVHSKASQLLARSSLSHYLGISLDLQLQLEQLRGRTTMALDLPSSHLQCRIPLLPKRWDKEPLSSLRGFFPATVQPHKHCLRPICFPGYVPNSAVLQQMWLNAEPGASQDALWLWRPRPSQTQWQRKLLQWMGEKPGEEGEEDKKEEEEEKEDEELDWALASLSPHSNQQLDSWELEDQSAVDWTQEPRRRSCKVARTHPHPWHRHGSLLLDEHYGHLPKFLHFFIYQTWFKKLFPIFSLQAYPEAGTIEGLASLLVALLEKTTWVDRVHILQVLLRLLPNMSSDLQGQLQGLLVHLLNLDQPPSLQDQTQKKFVILALQLLLACSLESRDVVLELMSYFLYSPVHCRPELKKLLHGLGLQDPEGFLFKEMMTWVQGPDLDSKAGLRTCCHQKLEDMIQELQETPSQTSVVSGAPTRASVIPSGTSWSASGIFGRLSQVSEVPLMVVSPAEPHSLAPELQAQRMLAPKRSWGTPQLRLRVLSETLKSFCLEPEARLHPAGPAQLPGEPPPLEETDWSHSQLLDLGPIDALNFFCEQLRAQQRSSLQEKAAHPHPPEPYTVAPVPDMVVPPPREHWYHPILRLQEAKPQRSARSAMRLRGPMRSRLCAGRTLDGPIRTLKLPLPRVEPQPFPLDWPMPPRPLPPRLLQPALQRYFLPADADPDTYS |
Proteomic databases
PTM databases
Expression
Structure
Family & Domains
Features
Showing features for repeat, region, coiled coil, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Repeat | 187-233 | WD 1 | ||||
Sequence: SEQGVGRAPGWAPTCCLPVPDLRLLLVAEMNSSLALWQFRSGGRRLV | ||||||
Repeat | 290-329 | WD 2 | ||||
Sequence: LHKTTISDLAYCEEVEAMVTASRDSTVKVWEADWQIRMVF | ||||||
Repeat | 331-370 | WD 3 | ||||
Sequence: GHTGPVTAMTVLPNTTLVLSASQDGTLRTWDLQAAAQVGE | ||||||
Repeat | 552-592 | WD 4 | ||||
Sequence: ELRCSSVACAWKNKNRYLPVVGHTDGTLSVLEWLSSKTVFQ | ||||||
Repeat | 594-633 | WD 5 | ||||
Sequence: EAHSPGPVVAIASTWNSIVSSGGDLTVKMWRVFPYAEESL | ||||||
Repeat | 687-726 | WD 6 | ||||
Sequence: DPTDHITGLCCCPTLKLYACSSLDCTVRIWTAENRLLRLL | ||||||
Region | 1090-1112 | Disordered | ||||
Sequence: GEKPGEEGEEDKKEEEEEKEDEE | ||||||
Coiled coil | 1094-1118 | |||||
Sequence: GEEGEEDKKEEEEEKEDEELDWALA | ||||||
Compositional bias | 1098-1112 | Acidic residues | ||||
Sequence: EEDKKEEEEEKEDEE | ||||||
Region | 1453-1472 | Disordered | ||||
Sequence: LHPAGPAQLPGEPPPLEETD |
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence & Isoform
- Sequence statusComplete
This entry describes 2 isoforms produced by Alternative splicing.
A6NE52-1
This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
- Name1
- Length1,622
- Mass (Da)180,307
- Last updated2008-05-20 v2
- Checksum3991010D04BFD01A
A6NE52-2
- Name2
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
E9PKB8 | E9PKB8_HUMAN | WDR97 | 837 |
Sequence caution
Features
Showing features for sequence conflict, alternative sequence, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Sequence conflict | 430 | in Ref. 1; BAB47504 | ||||
Sequence: V → L | ||||||
Alternative sequence | VSP_033425 | 809-837 | in isoform 2 | |||
Sequence: SEALSLIHRRRATSQHLVPKEDLDAIVAR → RSHGGLLSPPGGPPFPLWVGAWRCGALWS | ||||||
Alternative sequence | VSP_033426 | 838-1622 | in isoform 2 | |||
Sequence: Missing | ||||||
Compositional bias | 1098-1112 | Acidic residues | ||||
Sequence: EEDKKEEEEEKEDEE |
Keywords
- Coding sequence diversity
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AB058778 EMBL· GenBank· DDBJ | BAB47504.1 EMBL· GenBank· DDBJ | mRNA | Sequence problems. | |
AC104592 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. |