A6MVV0 · A6MVV0_RHDSA
- ProteinFerredoxin-thioredoxin reductase, catalytic chain
- GeneftrB
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids112 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalytic subunit of the ferredoxin-thioredoxin reductase (FTR), which catalyzes the two-electron reduction of thioredoxins by the electrons provided by reduced ferredoxin.
Catalytic activity
- [thioredoxin]-disulfide + 2 reduced [2Fe-2S]-[ferredoxin] + 2 H+ = [thioredoxin]-dithiol + 2 oxidized [2Fe-2S]-[ferredoxin]
RHEA-COMP:10700 CHEBI:50058 Position: n/n+3+ 2 RHEA-COMP:10001 + 2 CHEBI:15378 = RHEA-COMP:10698 CHEBI:29950 Position: nCHEBI:29950 Position: n+3+ 2 RHEA-COMP:10000
Cofactor
Note: Binds 1 [4Fe-4S] cluster.
Features
Showing features for binding site, active site, site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 53 | [4Fe-4S] cluster (UniProtKB | ChEBI) | ||||
Sequence: C | ||||||
Active site | 55 | Nucleophile | ||||
Sequence: C | ||||||
Binding site | 72 | [4Fe-4S] cluster (UniProtKB | ChEBI) | ||||
Sequence: C | ||||||
Binding site | 74 | [4Fe-4S] cluster (UniProtKB | ChEBI) | ||||
Sequence: C | ||||||
Binding site | 83 | [4Fe-4S] cluster (UniProtKB | ChEBI) | ||||
Sequence: C | ||||||
Site | 84 | Increases the nucleophilicity of the active site Cys | ||||
Sequence: H |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | chloroplast | |
Molecular Function | 4 iron, 4 sulfur cluster binding | |
Molecular Function | ferredoxin-thioredoxin reductase activity | |
Molecular Function | metal ion binding | |
Molecular Function | oxidoreductase activity, acting on iron-sulfur proteins as donors |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameFerredoxin-thioredoxin reductase, catalytic chain
- EC number
- Short namesFTR-C
- Alternative names
Gene names
Encoded on
- Chloroplast
Organism names
- Strain
- Taxonomic lineageEukaryota > Cryptophyceae > Pyrenomonadales > Pyrenomonadaceae > Rhodomonas
Accessions
- Primary accessionA6MVV0
Subcellular Location
UniProt Annotation
GO Annotation
Keywords
- Cellular component
PTM/Processing
Features
Showing features for disulfide bond.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Disulfide bond | 55↔85 | Redox-active | ||||
Sequence: CRHYDDKEAEVSSAYWNCPCVPMRERKECHC |
Keywords
- PTM
Interaction
Subunit
Heterodimer of subunit A (variable subunit) and subunit B (catalytic subunit). Heterodimeric FTR forms a complex with ferredoxin and thioredoxin.
Structure
Sequence
- Sequence statusComplete
- Length112
- Mass (Da)12,805
- Last updated2007-07-24 v1
- Checksum3B60303A67CC8421
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
EF508371 EMBL· GenBank· DDBJ | ABO70831.1 EMBL· GenBank· DDBJ | Genomic DNA |