A6JLB5 · A6JLB5_RAT

  • Protein
    T-cell lymphoma invasion and metastasis 1
  • Gene
    Tiam1
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Predicted
  • Annotation score
    5/5

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentaxonal growth cone
Cellular Componentcell-cell contact zone
Cellular Componentcell-cell junction
Cellular Componentcytosol
Cellular Componentdendritic spine
Cellular Componentextrinsic component of postsynaptic density membrane
Cellular Componentglutamatergic synapse
Cellular Componentkinocilium
Cellular Componentmain axon
Cellular Componentmicrotubule
Cellular Componentneuronal cell body
Cellular Componentpericentriolar material
Cellular Componentplasma membrane
Cellular Componentruffle membrane
Cellular Componentsomatodendritic compartment
Cellular Componentsynapse
Molecular Functionephrin receptor binding
Molecular Functionguanyl-nucleotide exchange factor activity
Molecular Functionkinase binding
Molecular Functionmicrotubule binding
Molecular Functionphospholipid binding
Molecular Functionreceptor tyrosine kinase binding
Biological Processbrain-derived neurotrophic factor receptor signaling pathway
Biological Processcardiac muscle hypertrophy
Biological Processcell migration
Biological Processcell-matrix adhesion
Biological Processephrin receptor signaling pathway
Biological Processneuron projection extension
Biological Processpositive regulation of axonogenesis
Biological Processpositive regulation of cell migration
Biological Processpositive regulation of cell population proliferation
Biological Processpositive regulation of dendritic spine morphogenesis
Biological Processpositive regulation of neuron projection development
Biological Processpositive regulation of Schwann cell chemotaxis
Biological Processprotein localization to membrane
Biological Processprotein-containing complex assembly
Biological ProcessRac protein signal transduction
Biological Processregulation of dopaminergic neuron differentiation
Biological Processregulation of epithelial to mesenchymal transition
Biological Processregulation of ERK1 and ERK2 cascade
Biological Processregulation of insulin secretion involved in cellular response to glucose stimulus
Biological Processregulation of modification of postsynaptic actin cytoskeleton
Biological Processregulation of non-canonical Wnt signaling pathway
Biological Processregulation of postsynapse organization
Biological Processresponse to cocaine
Biological Processsmall GTPase-mediated signal transduction

Names & Taxonomy

Protein names

  • Submitted names
    • T-cell lymphoma invasion and metastasis 1

Gene names

    • Name
      Tiam1
    • ORF names
      rCG_58779

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • BN
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Rattus

Accessions

  • Primary accession
    A6JLB5

Proteomes

Organism-specific databases

Family & Domains

Features

Showing features for region, compositional bias, domain, coiled coil.

TypeIDPosition(s)Description
Region1-70Disordered
Compositional bias24-45Basic residues
Compositional bias48-70Polar residues
Compositional bias304-327Polar residues
Region304-378Disordered
Compositional bias339-378Polar residues
Region392-421Disordered
Domain438-546PH
Coiled coil552-579
Domain764-831RBD
Domain844-907PDZ
Region932-1033Disordered
Compositional bias953-974Polar residues
Compositional bias997-1033Polar residues
Domain1039-1233DH
Region1455-1481Disordered

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,590
  • Mass (Da)
    177,162
  • Last updated
    2023-06-28 v1
  • Checksum
    47A759B4DFAD2CBA
MGNAESQNVDHEFYGEKHASLGRKHTSRSLRLSHKTRRTRHASSGKAIHRNSEVSTRSSSTPSIPQSLAENGLEPFSQEGALDDFGDPIWVDRVDMGLRPVSYTDSSVTPSVDGSIVLTAASVQSMPDSEESRLYGDDAAYLAEGGRRQRPYTSNGPTFMETASFKKKRSKSADIWREDSLEFSLSDLSQEHLTSNEEILGSAEEKDCEEARGMETGASPRQLSTCQRANSLGDLYAQKNSGVKANGGPRNRFSSYCRNLVSDIPDLAKHKMPPAAVETPTYSNYNTLPCRKSHCLSEGATNPQISLSKSMQGRRAKTTQDVNTGEGSEFADSGIEGATTDTDLLSRRSNATNSSYSPPTGRAFVGSDSGSSSTGDAARQGVYENFRRELEMSTTNSESLEEAGSAHSDEQSSGTLSSPGQSDILLTAAQGTVRKAGALAVKNFLVHKKNKKVESATRRKWKHYWVSLKGCTLFFYESDGRSGIDHNSVPKHAVWVENSIVQAVPEHPKKDFVFCLSNSLGDAFLFQTTSQTELENWITAIHSACAAAVARHHHKEDTLRLLKSEIKKLEQKIDMDEKMKKMGEMQLSSVTDAKKKKTILDQIFVWEQNLEQFQMDLFRFRCYLASLQGGELPNPKRLLGFASRPTKVAMGRLGIFSVSSFHALVAARTGEIGVRRRTQAMSRSASKRRSRFSSLWGLDTTSKKKQGRPTINQVFGEGTDAVKRSLEGIFDDSVPDGKREKEVVLPSVHQHNPDCDIWVHEYFTPSWFCLPNNQPALTVVRPGDTARDTLELICKAHQLDHSAHYLRLKFLMENKMQFYVPQPEEDIYELLYKEIEICPKVTQNIHIEKSDAAADNYGFLLSSVDEDGVRRLYVNSVKETGLASKKGLKAGDEILQINNRAAGTLNSSMLKDFLSQPSLGLLVRTYPEPEGGVELLENPPHRVDGPVDLGESPLTFLTSNPGHSLSSEQGSSAETAPEEGEGPDLESSDETDHSSKSTEQVTAFCRSLHEMSPSDSSPSPQDATSPQLATTRQLSDADKLRKVICELLETERTYVKDLNCLMERYLKPLQKETFLTQDELDVLFGNLTEMVEFQVEFLKTLEDGVRLVPDLEKLEKVDQFKKVLFSLGGSFLYYADRFKLYSAFCASHTKVPKVLVKAKTDTAFKAFLDAQNPRQQHSSTLESYLIKPIQRVLKYPLLLRELFALTDAESEEHYHLDVAIKTMNKVASHINEMQKIHEEFGAVFDQLIAEQTGEKKEVADLSMGDLLLHTSVIWLNPPASLGKWKKEPELAAFVFKTAVVLVYKDGSKQKKKLVGSHRLSIYEEWDPFRFRHMIPTEALQVRALPSADAEANAVCEIVHVKSESEGRPERVFHLCCSSPESRKDFLKSVHSILRDKHRRQLLKTESLPSAQQYVPFGGKRLCALKGARPAMSRAVSAPSKSLGRRRRRLARNRFTIDSDAISASSPEKEPQQPPGGGDTDRWVEEQFDLAQYEEQDDIKETDILSDDDEFCESAKGASVDIDLQEQLQAASISQRARGRKTLDSHASRMTQLKKQAALSGINGGLESASEEVIWVRREDFAPSRKLNTEI

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias24-45Basic residues
Compositional bias48-70Polar residues
Compositional bias304-327Polar residues
Compositional bias339-378Polar residues
Compositional bias953-974Polar residues
Compositional bias997-1033Polar residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CH473989
EMBL· GenBank· DDBJ
EDM10680.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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