A6JFK0 · A6JFK0_RAT

Function

function

Microtubule-associated protein regulating the stability and length of the microtubule-based axoneme of photoreceptors. Required for the differentiation of photoreceptor cells, it plays a role in the organization of the outer segment of rod and cone photoreceptors ensuring the correct orientation and higher-order stacking of outer segment disks along the photoreceptor axoneme.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentaxoneme
Cellular Componentciliary tip
Cellular Componentcilium
Cellular Componentmicrotubule associated complex
Cellular Componentphotoreceptor cell cilium
Cellular Componentphotoreceptor connecting cilium
Cellular Componentphotoreceptor inner segment
Cellular Componentphotoreceptor outer segment
Molecular Functionmicrotubule binding
Biological Processaxoneme assembly
Biological Processcellular response to light stimulus
Biological Processintracellular signal transduction
Biological Processphotoreceptor cell development
Biological Processphotoreceptor cell maintenance
Biological Processphotoreceptor cell outer segment organization
Biological Processpositive regulation of non-motile cilium assembly
Biological Processretina development in camera-type eye
Biological Processretina morphogenesis in camera-type eye
Biological Processretinal cone cell development
Biological Processretinal rod cell development
Biological Processvisual perception

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Oxygen-regulated protein 1

Gene names

    • Name
      Rp1
    • ORF names
      rCG_30348

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • BN
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Rattus

Accessions

  • Primary accession
    A6JFK0

Proteomes

Organism-specific databases

Interaction

Subunit

Interacts (via the doublecortin domains) with microtubules. Interacts with RP1L1. Interacts with MAK.

Structure

3D structure databases

Family & Domains

Features

Showing features for region, domain, compositional bias.

TypeIDPosition(s)Description
Region1-27Disordered
Domain35-117Doublecortin
Domain157-236Doublecortin
Region638-662Disordered
Region910-991Disordered
Compositional bias919-947Polar residues
Compositional bias962-979Polar residues
Region1393-1460Disordered
Compositional bias1411-1427Basic and acidic residues
Compositional bias1428-1443Polar residues
Region1554-1577Disordered
Region1820-1842Disordered
Compositional bias1824-1839Basic and acidic residues

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    2,125
  • Mass (Da)
    237,897
  • Last updated
    2023-06-28 v1
  • Checksum
    D27F226B0EA27B72
MSETPSTSFSMIRLTSSEGQVPSRHSNVTHPTVAKRISFYKSGDPQFGGVRVVVNPRSFKTFDALLDNLSRKVPLPFGVRNISTPRGRHSITKLEELEDGESYVCSHNKKVLPVDLDKARRRPRPWLSSRSISTHVKLRSATATMPTTAPGLFRAPRRLVVFRNGDPKTRRVVLLSRRITQSFEAFLQYLTQVMQYPVAKLYATDGRKVPSLQAVILSSGAVVAAGREPFKPGNYDIQKYLLPVKLPGISHRVHRKGKAKIEKRKMSTHSVPRPQTDSLASEKTYDCFSDFSVAPENYLALETHDSQTLSTYPSEDGVEKSIVFNQDGTMTVVMKVRFKIKEETVKWTTTVNRADLSNDDEKSKISSYPGKTEDRSSSLKLVVPCSLSEDITDTTQQGSLTEEENTQMTEQQALSSSSAGWENASMEVGIQGSQKQVKHFYRPPTPGPRRMRQKKSVIGTVTVVSETEVQEKQFSYREEREVGEKSKYHMFTHSCSKMSSVSNKLVQISSDDERESALERTKESGPLKSHAINAGAIEITSQRVLKMCHNNALASTVPENSVVEEGTDDSAISGKATIKHFRTCGNANDSFSSTTADTTLTSGNNCPNVRTISEVPSVGSPVLTTGLVNEFAHCGLTEHPGNGRQISSPFASKKKKKSQQRMITSKDKKKVIETKGIPNKVGKIHRAGTIAQVVLLQDSGGLDKEGRVREEELDTSPMVIESHDIFPKGNSKFSKNFHKNKLNTVQNPKTQKLLAKRKSRPLKIKSIGELRKQETGQEDKVFLHSESKLCESNLEKQSLLHVFSSLEEDQKALHRSQSQVETVTENWKGMTKKSLVPKVNDLHVTVRNQRKQKGVKLKSGATVSEQHIATRADPLASLKKPDLTEGIPHHSVKSYIQRWLQNINPYPDFEHRKSAPLGQDRSNVVNYNSNGFPENNLPTTSSKGKSFLMESNKRKTKNANWKGNKNQETSKSLVVKDNGEQPNKHSCESQDESLYDSYLGPLHDNCTLSQTSINDPCTKSHLSTEKSRPEVKLVYQEMNFSTKRQTLEVAIQVDTMGENVPKDLLALLLQHLEAFIPNNQKHQNGISQLPGSLAEVVFPSAIYNSSTNLLLAWLLVLNLKRNMNSFCQSDAPKTTSRSSETAALLDVLKHVAITEEADDLKAAVANLVESTKTCSGPSGREQDTAPANCIAASLHSVDKCKENKSTQKSLLDEGYSVRGDCGPELCVLEMVSKSNNTPSEGHTVSMTYPPKGVNNQNDALFTSNDSSTMSQRSTHNASFLGEACLLTDSLCSHKACAQKDNIYEAACLSDETHIPIRDCKTIEFVNSKENKCTDNLELTEEIKTVDKVPKDLNILADSIDKNESDISTSSQNVNKLSSQGIFLSKTHLDSDKDYSPLEEFQNCPPKKIVNKKKSVSSDKEDSRTSEEPRSITNSVTSSERNATSELESFEESESQDTGIFNMKVRTEEKAAKESMQKESEARMSLELINISGRNIIEQGRRNTAFLETTGRGQVTPPSLVFCYDSNKNTEKEMSVGETKMRVKKIVDSMENESYTDSSLNCNKQHRSPGTLDWSDYGSDSESRYPCKALSYEHSDDTGQEREYPRGIVRRAIEKLYGKAEIIKPPFFHGSIHKSQVCPYNPVEVPCVKKTHFYESECQSLVSSEQVSRSSLMLQEFQEERQSEVDANGMGDSFGDSSIEKVTKPSEHGRVFMEKEKGKLIDNGKWLLRENHLWRVSLDNPGMYGNADTTSVDTLMDKNSIEVPYSHFGELAPGPTMAELSSSEIEEMTQPLEVKCNYFNFPHGSDSEPFGEDFLDAQNTNCPKEKIPNHHKEEKRNSPSERTCTPVTQTFASAGNKVHPVCSDVIKTQPLPGSSITHGALQEGDSLDKLYALCGQHCPILTVIIQPVNEEDRGFAYRKDSDIENSLGFQLWMEIYPFLLQSKKNMFTSESRKVNVGKQFTDNAIGNLCDRLYFKNMIDLVDKRANSLREEVNLNKVQLYLKKRFSDLLPSSSLVVWDMNSVSLTPSNWTDNFKSVDENNFINRFQNSRKNPNQVVREENSCQFHWELFGQVYLLDICQVEKSLHIKTRSKLEIYYILGGEVLFIWEEENQLNIIDIESPNDQNDL

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias919-947Polar residues
Compositional bias962-979Polar residues
Compositional bias1411-1427Basic and acidic residues
Compositional bias1428-1443Polar residues
Compositional bias1824-1839Basic and acidic residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CH473984
EMBL· GenBank· DDBJ
EDM11596.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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