A6J991 · A6J991_RAT

Function

function

Cytochromes P450 are a group of heme-thiolate monooxygenases.

Catalytic activity

Cofactor

heme (UniProtKB | Rhea| CHEBI:30413 )

Features

Showing features for binding site.

149950100150200250300350400450
TypeIDPosition(s)Description
Binding site439Fe (UniProtKB | ChEBI) of heme (UniProtKB | ChEBI); axial binding residue

GO annotations

AspectTerm
Cellular Componentcytoplasm
Cellular Componentendoplasmic reticulum membrane
Cellular Componentintracellular membrane-bounded organelle
Molecular Functionarachidonic acid epoxygenase activity
Molecular Functionheme binding
Molecular Functionhydro-lyase activity
Molecular Functioniron ion binding
Molecular Functionmonooxygenase activity
Molecular Functionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
Molecular Functionthromboxane-A synthase activity
Biological Processepoxygenase P450 pathway
Biological Processicosanoid metabolic process
Biological Processprostaglandin metabolic process
Biological Processretinoic acid metabolic process
Biological Processxenobiotic metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Cytochrome P450
  • EC number

Gene names

    • Name
      Cyp2s1
    • ORF names
      rCG_53865

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • BN
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Rattus

Accessions

  • Primary accession
    A6J991

Proteomes

Organism-specific databases

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane297-318Helical

Keywords

PTM/Processing

Features

Showing features for signal, chain.

TypeIDPosition(s)Description
Signal1-23
ChainPRO_503995265324-499Cytochrome P450

Structure

3D structure databases

Family & Domains

Sequence similarities

Belongs to the cytochrome P450 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    499
  • Mass (Da)
    55,548
  • Last updated
    2023-06-28 v1
  • Checksum
    36C42D352F6B44CE
MEAASTWALLLALLLLLLALTLPRTPARGQLPPGPTPLPLLGNLLQLRPGALYSGFLRLSKKYGPVFTVHLGPWRRVVVLVGHDAIREALGGQAEEFSGRGTLATLDKTFDGHGVFFANGERWKQLRKFTLLALRDLGMGKREGEELIQEEVQNLVKAFQRTEGRPFNPSMLLAQATSNVVCSLIFGIRLPYEDKEFQAVIQAASGTLLGISSPWGQAYEMFSWLLQPLPGPHTQLQHHLGTLAAFTIQQVQRHQGRSHTSGPARDVVDAFLQKMAQEKEDPGTEFTEKNLLMTVTYLLFAGTMTIGATIRYALLLLLKYPQVQKRVREELIQELGPSRTPSLSDRVRLPYTDAVLHEAQRLLALVPMGMPHTVTKTTSFRGYTLPKGTEVFPLIGSVLHDPAVFRNPEEFHPSRFLDDDGRIRKHEAFLPYSLGKRVCLGEGLARAELWLFFTSILQAFSLDTPCPPGDLSLKPAVRGLFNIPPDFQLQVWPTGDQSR

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CH473979
EMBL· GenBank· DDBJ
EDM07993.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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