A6J659 · A6J659_RAT
- ProteinAmmonium transporter Rh type B
- GeneRhbg
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids455 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- CO2(out) = CO2(in)This reaction proceeds in the forward direction.
- NH4+(in) = NH4+(out)This reaction proceeds in the forward and the backward directions.
- methylamine(out) = methylamine(in)This reaction proceeds in the forward direction.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | basolateral plasma membrane | |
Cellular Component | lateral plasma membrane | |
Molecular Function | ammonium channel activity |
Names & Taxonomy
Protein names
- Recommended nameAmmonium transporter Rh type B
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Rattus
Accessions
- Primary accessionA6J659
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Basolateral cell membrane ; Multi-pass membrane protein
Cell membrane ; Multi-pass membrane protein
Lateral cell membrane ; Multi-pass membrane protein
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 64-82 | Helical | ||||
Sequence: VHVMVFVGFGFLMVFLQRY | ||||||
Transmembrane | 89-111 | Helical | ||||
Sequence: FTFLVATFTLQWATLLQGFLHSF | ||||||
Transmembrane | 123-142 | Helical | ||||
Sequence: LINADFCAGAVLISFGAVLG | ||||||
Transmembrane | 149-171 | Helical | ||||
Sequence: LLLMALLEAVLFSVNEFILLSLL | ||||||
Transmembrane | 177-198 | Helical | ||||
Sequence: GGSMTIHTFGAYFGLFLSRVLY | ||||||
Transmembrane | 210-230 | Helical | ||||
Sequence: TSVYNSDLFAMIGTIFLWVFW | ||||||
Transmembrane | 250-269 | Helical | ||||
Sequence: NTYYSLTASTLSTFALSALV | ||||||
Transmembrane | 302-322 | Helical | ||||
Sequence: FGALAAGFLAGTVSTLGYKFF | ||||||
Transmembrane | 342-360 | Helical | ||||
Sequence: HGMPGLLGAILGVLVAALA | ||||||
Transmembrane | 391-412 | Helical | ||||
Sequence: LFGMFVTLVFASVGGSLGGLLL |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-24 | |||||
Sequence: MARIPRHRRLVLPLLCLLFQGATS | ||||||
Chain | PRO_5039911114 | 25-455 | Ammonium transporter Rh type B | |||
Sequence: LLFAIFVRYNHETDAALWHWGNHSNVDNEFYFRYPSFQDVHVMVFVGFGFLMVFLQRYGFSSVGFTFLVATFTLQWATLLQGFLHSFHGGHIHIGVESLINADFCAGAVLISFGAVLGKTGPAQLLLMALLEAVLFSVNEFILLSLLGVRDAGGSMTIHTFGAYFGLFLSRVLYRSQLEKSRHRQTSVYNSDLFAMIGTIFLWVFWPSFNSAPTALGDGQHRTVVNTYYSLTASTLSTFALSALVSGDGRLDMVHIQNAALAGGVVVGTASEMMLTPFGALAAGFLAGTVSTLGYKFFTPILESRFKLQDTCGVHNLHGMPGLLGAILGVLVAALATHEAYGDGLQTVFPLIAKGQRSATSQAMYQLFGMFVTLVFASVGGSLGGLLLKLPFLDSPPDSQCFEDQVYWEVPGEQEAETQRPLRTEEPDTQA |
Keywords
- PTM
Interaction
Subunit
Interacts (via C-terminus) with ANK2 and ANK3; required for targeting to the basolateral membrane.
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 23-414 | Ammonium transporter AmtB-like | ||||
Sequence: TSLLFAIFVRYNHETDAALWHWGNHSNVDNEFYFRYPSFQDVHVMVFVGFGFLMVFLQRYGFSSVGFTFLVATFTLQWATLLQGFLHSFHGGHIHIGVESLINADFCAGAVLISFGAVLGKTGPAQLLLMALLEAVLFSVNEFILLSLLGVRDAGGSMTIHTFGAYFGLFLSRVLYRSQLEKSRHRQTSVYNSDLFAMIGTIFLWVFWPSFNSAPTALGDGQHRTVVNTYYSLTASTLSTFALSALVSGDGRLDMVHIQNAALAGGVVVGTASEMMLTPFGALAAGFLAGTVSTLGYKFFTPILESRFKLQDTCGVHNLHGMPGLLGAILGVLVAALATHEAYGDGLQTVFPLIAKGQRSATSQAMYQLFGMFVTLVFASVGGSLGGLLLKL |
Sequence similarities
Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length455
- Mass (Da)49,731
- Last updated2023-06-28 v1
- Checksum725815539CC2F19A