A6IBA2 · A6IBA2_RAT

  • Protein
    Xeroderma pigmentosum, complementation group C (Predicted)
  • Gene
    Xpc
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    4/5

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Cellular Componentnucleotide-excision repair complex
Cellular Componentnucleotide-excision repair factor 2 complex
Cellular Componentnucleus
Cellular Componentsite of DNA damage
Cellular ComponentXPC complex
Molecular Functiondamaged DNA binding
Molecular FunctionDNA damage sensor activity
Molecular Functionprotein-containing complex binding
Molecular FunctionRNA polymerase II-specific DNA-binding transcription factor binding
Molecular Functionsingle-stranded DNA binding
Molecular Functiontranscription coactivator activity
Biological ProcessDNA damage response
Biological ProcessDNA repair
Biological Processmismatch repair
Biological Processmitotic intra-S DNA damage checkpoint signaling
Biological Processnucleotide-excision repair
Biological Processpositive regulation of DNA-templated transcription
Biological Processpyrimidine dimer repair by nucleotide-excision repair
Biological Processregulation of mitotic cell cycle phase transition
Biological Processresponse to auditory stimulus
Biological Processresponse to UV-B
Biological Processresponse to xenobiotic stimulus
Biological ProcessUV-damage excision repair

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • Xeroderma pigmentosum, complementation group C (Predicted)

Gene names

    • Name
      Xpc
    • Synonyms
      Xpc_predicted
    • ORF names
      rCG_56286

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • BN
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Rattus

Accessions

  • Primary accession
    A6IBA2

Proteomes

Organism-specific databases

Subcellular Location

Family & Domains

Features

Showing features for region, compositional bias, domain.

TypeIDPosition(s)Description
Region1-133Disordered
Compositional bias12-44Basic and acidic residues
Compositional bias82-121Basic and acidic residues
Region325-515Disordered
Compositional bias337-354Polar residues
Compositional bias355-369Basic and acidic residues
Compositional bias395-411Basic and acidic residues
Compositional bias445-460Basic and acidic residues
Compositional bias467-503Polar residues
Domain624-676Rad4 beta-hairpin
Domain678-738Rad4 beta-hairpin
Domain745-819Rad4 beta-hairpin
Region867-933Disordered
Compositional bias902-933Basic and acidic residues

Sequence similarities

Belongs to the XPC family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    933
  • Mass (Da)
    104,860
  • Last updated
    2023-06-28 v1
  • Checksum
    01C1B5D7CC50669F
MARKRTAGGKRRKRGQEAEDNKATRPEESDADDFEDEKQKPPRKCFLPKVSQGKRKRDCSDPGDPTNGAAKKKVAKATTKSKNLKAVKEEALSDDGDDFRDSLSNCRKAKKHPKREVVDQGTDEDDSEDDWEEVEELTEPVLDMGENSATSRSDLPVKAVEIEIETPEQAKARERSEKIKMEFETYLRRMMKRFNKEVQENMHKVHLLCLLASGFYRNSICQQPDLLAIGLSIIPIRFTKVPLQDRDVYYLSNLVKWFIGTFTVNADLSASEQDSLQTTLERRIAIYSARDNEELVHIFLLILRALQLLTRLVLSLQPIPLKSAVAKGKKSSKETSLEGPGDSSEPSSNIPESHNKPKTSKRIKQEETLSEGSGKANARGKRGTATAGSRQQRKPSCSEGEEAKQEIQSHPQAQKRRVAAKVSYKEESESDGAGSGSDFELSSGEGQHSSDEDCKPGPRKQKRASAPQRSKAGSKSASKTQSGSQWEPPSFSVASSSSSACKRGKKISCGGEETDDRKAAGVDQWLEVFCEPQAKWVCVDCVHGVVGQPVACYKYATKPMTYVVGIDSDGWVRDVTQRYDPAWMTATRKCRVDAEWWAETLRPYRSPLTEREKKEDQEFQAKHLDQPLPTSISTYKNHPLYALKRHLLKFQAIYPESAAVLGYCRGEAVYSRDCVHTLHSRDTWLKQARVVRLGEVPYKMVKGFSNRARKARLSEPQLHDHNDLGLFGHWQTEEYQPPVAVDGKVPRNEFGNVYLFLPSMMPIGCVQMNLPNLHRVARKLGIDCVQAITGFDFHGGYCHPVTDGYVVCEEFRDVLLAAWENEQALIEKKEKEKKEKRALGNWKLLVRGLLIRERLKLRYGAKSEAAAPHANAGGGLSSDEEEGTSSQAEAARVLAASWPQNRETKEEQKPDYTKMTRRRRAAEASHLFPFEKL

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias12-44Basic and acidic residues
Compositional bias82-121Basic and acidic residues
Compositional bias337-354Polar residues
Compositional bias355-369Basic and acidic residues
Compositional bias395-411Basic and acidic residues
Compositional bias445-460Basic and acidic residues
Compositional bias467-503Polar residues
Compositional bias902-933Basic and acidic residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CH473957
EMBL· GenBank· DDBJ
EDL91370.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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