A6HYJ3 · A6HYJ3_RAT

  • Protein
    Two pore segment channel 2 (Predicted), isoform CRA_a
  • Gene
    Tpcn2
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Predicted
  • Annotation score
    4/5

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytosol
Cellular Componentendolysosome membrane
Cellular Componentendosome membrane
Cellular Componentlysosomal membrane
Cellular Componentlysosome
Cellular Componentmelanosome membrane
Molecular Functioncalcium channel activity
Molecular Functionidentical protein binding
Molecular Functionintracellularly phosphatidylinositol-3,5-bisphosphate-gated monatomic cation channel activity
Molecular Functionligand-gated sodium channel activity
Molecular FunctionNAADP-sensitive calcium-release channel activity
Molecular Functionphosphatidylinositol-3,5-bisphosphate binding
Molecular Functionprotein kinase binding
Molecular Functionvoltage-gated calcium channel activity
Biological Processcalcium-mediated signaling
Biological Processendocytosis involved in viral entry into host cell
Biological Processendosome to lysosome transport of low-density lipoprotein particle
Biological Processintracellular calcium ion homeostasis
Biological Processintracellular pH reduction
Biological Processlysosome organization
Biological Processnegative regulation of developmental pigmentation
Biological Processregulation of autophagy
Biological Processregulation of exocytosis
Biological Processrelease of sequestered calcium ion into cytosol
Biological Processresponse to vitamin D
Biological Processsmooth muscle contraction
Biological Processsodium ion transmembrane transport

Names & Taxonomy

Protein names

  • Submitted names
    • Two pore segment channel 2 (Predicted), isoform CRA_a

Gene names

    • Name
      Tpcn2
    • Synonyms
      Tpcn2_predicted
    • ORF names
      rCG_47337

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • BN
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Rattus

Accessions

  • Primary accession
    A6HYJ3

Proteomes

Organism-specific databases

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane67-87Helical
Transmembrane140-160Helical
Transmembrane201-223Helical
Transmembrane259-279Helical
Transmembrane396-415Helical
Transmembrane427-451Helical
Transmembrane463-483Helical
Transmembrane503-520Helical
Transmembrane541-561Helical
Transmembrane630-653Helical

Keywords

  • Cellular component

Structure

3D structure databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain72-256Ion transport
Domain391-656Ion transport

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    711
  • Mass (Da)
    81,395
  • Last updated
    2023-06-28 v1
  • Checksum
    2F3930DDB7D4EEEA
MAAEAQPLLGRDRGGGQAHSGADQELCIDQAVVFIEDAIKYRSIYHRLDAGSLWLYRWYYSNVCQRVLGFTIFLILALAFVEVPSSFTRTADVRYRSQPWQPPCGLTETIEALCLLVFLADLSVKGYLVGQAQLQQNLWLLAYFVVLVVSVVDWIVSLSLNCEESLRVRRLLRPFFLLQNSSMMKKTLKCIRWSLPEMASVGLLLTIHLCLFTVIGMLLFTIAEKDEAQNKERLTYFRNLPEALTSLLVLLTTSNNPDGSLFLMNLLTAIIYNQFRGYLMKSLQTSLFRRRLGARAAYEVLTLQAGPNGTTSELVGVNPENFLRVLQKTQLNKIHKQAIIQKVHSYEGRPILADEFQKLFDEVDKGIVKERPPKPQYQSPFLQTAQFIFSHRYFDYLGNLIALGNLLSICVFLVLDSNLLPGERNDFVLGILNYIFILYYLLELLFKVFALGLRGYLFYHSNVFDGLLTIILLVLEISTLAVYRLPHPGWKPEQYGPLSLWDMTRLVNILIVIRFLRIIPSIKPTAVVASTILGLIQNLRAFGGILVVVYYVFAMIGINLFRGVIVPPGNSSLVPDNSSAPCGSFEQLGYWPNNFDDFAAALITLWDVMVVNNWQVILEAYKHYSGPWSMVYFVLWWLVSSVIWINLFLALLLENFLHRWDPQGHKQLLVGTKQITYEMSVELMFRDILEEPKEEELMEKLHKHPHLHLCR

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CH473953
EMBL· GenBank· DDBJ
EDM12274.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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