A6HPH7 · A6HPH7_RAT
- ProteinTyrosine-protein kinase receptor TYRO3
- GeneTyro3
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids869 (go to sequence)
- Protein existenceInferred from homology
- Annotation score5/5
Function
Catalytic activity
- L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H+
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 529 | ATP (UniProtKB | ChEBI) | |||
Active site | 634 | Proton acceptor | |||
Binding site | 638 | ATP (UniProtKB | ChEBI) | |||
Binding site | 639 | Mg2+ (UniProtKB | ChEBI) | |||
Binding site | 652 | Mg2+ (UniProtKB | ChEBI) | |||
GO annotations
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameTyrosine-protein kinase receptor TYRO3
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Rattus
Accessions
- Primary accessionA6HPH7
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Single-pass type I membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 408-430 | Helical | |||
Keywords
- Cellular component
PTM/Processing
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 19-107 | Ig-like | |||
Domain | 118-199 | Ig-like | |||
Domain | 206-299 | Fibronectin type-III | |||
Domain | 304-395 | Fibronectin type-III | |||
Domain | 497-774 | Protein kinase | |||
Region | 793-816 | Disordered | |||
Region | 831-853 | Disordered | |||
Compositional bias | 841-853 | Polar residues | |||
Sequence similarities
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length869
- Mass (Da)95,094
- Last updated2023-06-28 v1
- MD5 ChecksumF7C3B70C297594FD37F769D778754983
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 841-853 | Polar residues | |||
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CH473949 EMBL· GenBank· DDBJ | EDL79928.1 EMBL· GenBank· DDBJ | Genomic DNA |