A6HMC4 · A6HMC4_RAT

  • Protein
    Endoplasmic reticulum junction formation protein lunapark
  • Gene
    Lnp_predicted
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Plays a role in determining ER morphology.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentendoplasmic reticulum tubular network membrane
Molecular Functionidentical protein binding
Molecular Functionmetal ion binding
Biological Processendoplasmic reticulum tubular network maintenance
Biological Processpositive regulation of endoplasmic reticulum tubular network organization

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Endoplasmic reticulum junction formation protein lunapark

Gene names

    • Name
      Lnp_predicted
    • ORF names
      rCG_27205

Organism names

  • Taxonomic identifier
  • Organism
  • Strains
    • BN
    • Sprague-Dawley
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Rattus

Accessions

  • Primary accession
    A6HMC4

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer; homodimerization requires the C4-type zinc finger motif and decreases during mitosis in a phosphorylation-dependent manner.

Family & Domains

Features

Showing features for compositional bias, region, domain.

TypeIDPosition(s)Description
Compositional bias1-26Basic and acidic residues
Region1-121Disordered
Compositional bias43-58Polar residues
Domain128-177Lunapark
Region184-302Disordered
Compositional bias198-222Polar residues
Compositional bias245-259Polar residues
Compositional bias276-302Polar residues

Domain

The C4-type zinc finger motif is necessary both for its ER three-way tubular junction localization and formation.

Sequence similarities

Belongs to the lunapark family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    302
  • Mass (Da)
    32,862
  • Last updated
    2023-06-28 v1
  • Checksum
    F700CBB02047B8BC
MEKETYKTAKLILERFDPDSKKAKEFEPPSAGAAATAKPGQEIRQRTAAQRNLSPAPANSNQGPPPQVPVSPGPSKDASAPGGPPERTVAPALPRRLGSPATSVPGMGLHPPGPPLARPVLPRERGALDRIVEYLVGDGPQNRYALICQQCFSHNGMALKEEFEYIAFRCAYCFFLNPARKTRPQAPRLPEFSFEKRQAVEGSSSTGPMLLESVPSPENQLTEDSLEEQDDLDNSTEQKDDKIPVTEQTNQVIEETSGPEGSEENQEETENEETSTNEAKSPVLRSDSVSNLELSEDSVVTK

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias1-26Basic and acidic residues
Compositional bias43-58Polar residues
Compositional bias198-222Polar residues
Compositional bias245-259Polar residues
Compositional bias276-302Polar residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CH473949
EMBL· GenBank· DDBJ
EDL79176.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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