A6HM56 · A6HM56_RAT

  • Protein
    Integrin, alpha 6, isoform CRA_a
  • Gene
    Itga6
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    5/5

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentadherens junction
Cellular Componentbasal part of cell
Cellular Componentbasal plasma membrane
Cellular Componentbasement membrane
Cellular Componentbasolateral plasma membrane
Cellular Componentcell surface
Cellular Componentexternal side of plasma membrane
Cellular Componentfilopodium
Cellular Componenthemidesmosome
Cellular Componentintegrin alpha6-beta1 complex
Cellular Componentintegrin alpha6-beta4 complex
Cellular Componentintegrin complex
Cellular Componentplasma membrane
Molecular Functioninsulin-like growth factor I binding
Molecular Functionintegrin binding
Molecular Functionlaminin binding
Molecular Functionneuregulin binding
Molecular Functionprotein-containing complex binding
Biological Processbrown fat cell differentiation
Biological Processcell adhesion mediated by integrin
Biological Processcell-cell adhesion
Biological Processcell-matrix adhesion
Biological Processcell-substrate adhesion
Biological Processcellular response to organic cyclic compound
Biological Processectodermal cell differentiation
Biological Processfilopodium assembly
Biological Processintegrin-mediated signaling pathway
Biological Processleukocyte migration
Biological Processlymphoid lineage cell migration
Biological Processnail development
Biological Processnegative regulation of extrinsic apoptotic signaling pathway
Biological Processodontogenesis of dentin-containing tooth
Biological Processpositive regulation of apoptotic process
Biological Processpositive regulation of cell migration
Biological Processpositive regulation of cell-cell adhesion
Biological Processpositive regulation of cell-substrate adhesion
Biological Processpositive regulation of neuron projection development
Biological Processpositive regulation of phosphorylation
Biological Processpositive regulation of transcription by RNA polymerase II
Biological Processskin morphogenesis

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • Integrin, alpha 6, isoform CRA_a

Gene names

    • Name
      Itga6
    • ORF names
      rCG_26750

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • BN
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Rattus

Accessions

  • Primary accession
    A6HM56

Proteomes

Organism-specific databases

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane1013-1037Helical

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for signal, chain.

TypeIDPosition(s)Description
Signal1-23
ChainPRO_503996169324-1073

Keywords

Structure

3D structure databases

Family & Domains

Features

Showing features for repeat, domain.

TypeIDPosition(s)Description
Repeat30-95FG-GAP
Repeat301-363FG-GAP
Repeat364-419FG-GAP
Repeat420-479FG-GAP
Domain464-624Integrin alpha first immunoglubulin-like
Domain626-791Integrin alpha second immunoglobulin-like
Domain797-1003Integrin alpha third immunoglobulin-like

Sequence similarities

Belongs to the integrin alpha chain family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,073
  • Mass (Da)
    119,479
  • Last updated
    2023-06-28 v1
  • Checksum
    0D7E9DD25C9428C1
MAVAGQLCLLYLSAGLLARLSTAFNLDTREDNVIRKSGDPGSLFGFSLAMHWQLQPEDKRLLLVGAPRAEALPLQKANRTGGLYSCDITSRGPCTRIVFDNDADPMSESKEDQWMGVTVQSQGPGGKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIEDDMDGGDWSFCDGRLRGHEKFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVGGETDHDESLVPVPANSYLGFSLDSGKGIVSKDDITFVSGAPRANHSGAVVLLKRDMKSAHLLLEYIFDGEGLASSFGYDVAVVDLNADGWQDIVIGAPQYFDRDGEVGGAVYVYINQQGRWSNVKPVRLNGTKDSMFGIAVKNIGDINQDGYPDIAVGAPYDDLGKVFIYHGSPTGIITKPTQVLEGTTPFFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVINILKTITVTPSRIDLRQKSMCGSPSGICLKVKACFEYTAKPSGYNPPISILGILEAEKERRKSGLSSRVQFRNQGSEPKYTQELTLNRQKQRACMEETLWLQENIRDKLRPIPITASVEIQEPSSRRRVNSLPEVLPILNSNEAKTVQTDVHFLKEGCGDDNVCNSNLKLEYKFGTREGNQDKFSYLPIQKGIPELVLKDQKDIALEITVTNGPSDPRNPRKDGDDAHEAKLIATFPDTLTYSAYRELRAFPEKQLSCVANQNGSQADCELGNPFKRNSSVTFYLILSTTEVTFDTTDLDINLKLETTSNQDNLAPITAKAKVVIELLLSVSGVAKPSQVYFGGTVVGEQAMKSEDEVGSLIEYEFRVINLGKPLKNLGTATLNIQWPKEISNGKWLLYLMKVESKGLEQVVCEPHNEINFLKLKESHNSRKKRELPEKQIDDSRKFSLFSERKYQTLNCSVNVRCVNIRCPLRGLDSKASLVLRSRLWNSTFLEEYSKLNYLDILVRASIDVTAAAQNIKLPHAGTQVRVTVFPSKTVAQYSGIAWWIILLAVLAGILMLALLVFLLWKCGFFKRNKKDHYDATYHKAEIHTQPSDKERLTSDA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CH473949
EMBL· GenBank· DDBJ
EDL79106.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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