Essential maintenance is planned to begin on Fri Jan 24 2025. The website may be temporarily unavailable. Please use our fallback: https://wwwdev.ebi.ac.uk/uniprot/front-end/fallback/ in case of any outage.

A5WFV1 · OBG_PSYWF

Function

function

An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for binding site.

140250100150200250300350400
TypeIDPosition(s)Description
Binding site166-173GTP (UniProtKB | ChEBI)
Binding site173Mg2+ (UniProtKB | ChEBI)
Binding site191-195GTP (UniProtKB | ChEBI)
Binding site193Mg2+ (UniProtKB | ChEBI)
Binding site213-216GTP (UniProtKB | ChEBI)
Binding site283-286GTP (UniProtKB | ChEBI)
Binding site315-317GTP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionGTP binding
Molecular FunctionGTPase activity
Molecular Functionmagnesium ion binding
Biological Processribosome biogenesis

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    GTPase Obg
  • EC number
  • Alternative names
    • GTP-binding protein Obg

Gene names

    • Name
      obg
    • Ordered locus names
      PsycPRwf_1601

Organism names

Accessions

  • Primary accession
    A5WFV1

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00003861671-402GTPase Obg

Interaction

Subunit

Monomer.

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for domain, region, compositional bias.

Type
IDPosition(s)Description
Domain1-159Obg
Domain160-334OBG-type G
Region382-402Disordered
Compositional bias386-402Acidic residues

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    402
  • Mass (Da)
    43,860
  • Last updated
    2007-07-10 v1
  • MD5 Checksum
    1FBF687AD994D95128DA9B789DC8EA10
MRFIDEAIVTVKAGDGGNGIVSFRREKYVPRGGPDGGDGGKGGDVFVVADDNTNTLVDYRYTRRYDAGRGENGHSKNCSGKGADNIYLRVPIGTTIVNNETGEVIGDLTEIGQELLIAKGGDGGLGNTHFKSSTNQAPRKATSGFEGELKELKFELKVVADVGLIGLPNAGKSTFIRQVSSAKPKVADYPFTTLVPNLGVVDVGVHRSFVMADIPGLIEGASEGAGLGIRFLKHVARTRRLLHILDIKPIDGSDPVENGRVILNELERFSPELANLPQILILNKIDQVPDADELNELCLHIVAELGWTGAVFRTSTLTGAGVDDVKYHLMNEIEREQEREEEDPMFAQAQKERFERLEAEVRLNTEEQKEAYRAARRAAREAAFNNELDDDDDDGVEVVYAP

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias386-402Acidic residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000713
EMBL· GenBank· DDBJ
ABQ94542.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help