A5WDN8 · A5WDN8_PSYWF

Function

function

DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.

Features

Showing features for binding site.

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TypeIDPosition(s)Description
Binding site118-125ATP (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytosol
Molecular FunctionATP binding
Molecular FunctionATP hydrolysis activity
Molecular FunctionATP-dependent DNA damage sensor activity
Molecular Functiondamaged DNA binding
Molecular Functionmetal ion binding
Molecular Functionmethyltransferase activity
Biological Processmethylation
Biological Processrecombinational repair

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    DNA repair protein RadA

Gene names

    • Name
      radA
    • Ordered locus names
      PsycPRwf_0827

Organism names

Accessions

  • Primary accession
    A5WDN8

Subcellular Location

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, motif, region.

Type
IDPosition(s)Description
Domain89-241RecA family profile 1
Motif278-282RadA KNRFG motif
Region376-482Lon-protease-like

Domain

The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

Sequence similarities

Belongs to the RecA family. RadA subfamily.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    482
  • Mass (Da)
    51,001
  • Last updated
    2007-07-10 v1
  • Checksum
    89D978B655E06657
MAKSKSSYVCQNCGAYFGKWAGQCSDCGEWNTLVEAPNVSLPHHNKSAAKGAMAAHTGPKMLAGAKSDRMNYSGSQSGVVTLGSVNVTFDTRLPTGISEFDRVLGGGLVAGSVVLIGGDPGIGKSTILLQTAANMADPESLSGSALYVTGEESLSQVAMRAQRLGLSSDHLKVMTETNVETICAALTQEQPAVAIIDSIQTIYTDAINSAPGGVSQIRESAAMLTRYAKQTGTALFLVGHVTKEGTLAGPRVLEHMVDTVLYFEGQSDSRFRMIRAVKNRFGAVNELGIFGMTDTGLKEVANPSAIFLSRYDKPISGSIVMVSREGTRPLLVEVQALVDDSAGQPRRMALGLDPQRLAMLLAVMHRHGGIHTSGQDVYVNVVGGVKVMETGSDLAVLLACASSIKERPLPSSLAVFGEVGLSGEIRPVPNGQERLKEAMKHGFTHAIVPKANAPKNLMGQFKGITVITADRLDDAIDRAFEI

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000713
EMBL· GenBank· DDBJ
ABQ93779.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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