A5UK92 · PYRH_METS3

Function

function

Catalyzes the reversible phosphorylation of UMP to UDP.

Catalytic activity

Activity regulation

Inhibited by UTP.

Pathway

Pyrimidine metabolism; CTP biosynthesis via de novo pathway; UDP from UMP (UMPK route): step 1/1.

Features

Showing features for binding site.

122520406080100120140160180200220
TypeIDPosition(s)Description
Binding site9-10ATP (UniProtKB | ChEBI)
Binding site43UMP (UniProtKB | ChEBI)
Binding site44ATP (UniProtKB | ChEBI)
Binding site48ATP (UniProtKB | ChEBI)
Binding site65UMP (UniProtKB | ChEBI)
Binding site113-119UMP (UniProtKB | ChEBI)
Binding site139ATP (UniProtKB | ChEBI)
Binding site145ATP (UniProtKB | ChEBI)
Binding site148ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular FunctionUMP kinase activity
Biological Process'de novo' CTP biosynthetic process
Biological ProcessUDP biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Uridylate kinase
  • EC number
  • Short names
    UK
  • Alternative names
    • Uridine monophosphate kinase
      (UMP kinase
      ; UMPK
      )

Gene names

    • Name
      pyrH
    • Ordered locus names
      Msm_0415

Organism names

Accessions

  • Primary accession
    A5UK92

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_10000539571-225Uridylate kinase

Interaction

Subunit

Homohexamer.

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the UMP kinase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    225
  • Mass (Da)
    24,507
  • Last updated
    2007-07-10 v1
  • Checksum
    E925AAD6C7CEFF35
MKIVVAIGGSILLKEYDCKKFQEYSEILKSLASEHEIFVVVGGGKPAREYIGVVRELGAGEAQCDDIGIEVTRINAKLLLSALGDAAYQKVPHNFQEALEYSATGKIIVMGGTEPAHSTDAVSAILAEYIHADKLINLTSVDGMYDKDPNKYEDAKLIKEITASEMIEFISGKDTKAGTYEFFDMTAIQMIKRSSLETVIANGYDSENLIKAINGEEVGTKVISK

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000678
EMBL· GenBank· DDBJ
ABQ86620.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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