A5UE44 · GLPK_HAEIE

Function

function

Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

Catalytic activity

Activity regulation

Inhibited by fructose 1,6-bisphosphate (FBP).

Pathway

Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.

Features

Showing features for binding site.

150350100150200250300350400450500
TypeIDPosition(s)Description
Binding site14ADP (UniProtKB | ChEBI)
Binding site14ATP (UniProtKB | ChEBI)
Binding site14sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site15ATP (UniProtKB | ChEBI)
Binding site16ATP (UniProtKB | ChEBI)
Binding site18ADP (UniProtKB | ChEBI)
Binding site84glycerol (UniProtKB | ChEBI)
Binding site84sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site85glycerol (UniProtKB | ChEBI)
Binding site85sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site136glycerol (UniProtKB | ChEBI)
Binding site136sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site246glycerol (UniProtKB | ChEBI)
Binding site246sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site247glycerol (UniProtKB | ChEBI)
Binding site268ADP (UniProtKB | ChEBI)
Binding site268ATP (UniProtKB | ChEBI)
Binding site311ADP (UniProtKB | ChEBI)
Binding site311ATP (UniProtKB | ChEBI)
Binding site315ATP (UniProtKB | ChEBI)
Binding site412ADP (UniProtKB | ChEBI)
Binding site412ATP (UniProtKB | ChEBI)
Binding site416ADP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular FunctionATP binding
Molecular Functionglycerol kinase activity
Biological Processglycerol catabolic process
Biological Processglycerol metabolic process
Biological Processglycerol-3-phosphate metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glycerol kinase
  • EC number
  • Alternative names
    • ATP:glycerol 3-phosphotransferase
    • Glycerokinase
      (GK
      )

Gene names

    • Name
      glpK
    • Ordered locus names
      CGSHiEE_08730

Organism names

Accessions

  • Primary accession
    A5UE44

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_10000207341-503Glycerol kinase

Structure

Family & Domains

Sequence similarities

Belongs to the FGGY kinase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    503
  • Mass (Da)
    56,069
  • Last updated
    2007-07-10 v1
  • Checksum
    28C7AC5850B9433F
MTDKKYIIALDQGTTSSRAVLLDHNANVVEIAQREFTQIYPRAGWVEHNPMEIWATQSSTLNEVVAKAGITSDEIAAIGITNQRETTIVWEKSTGTPVYNAIVWQCRRTADITDKLKADGHEEYIRNTTGLVVDPYFSGTKVKWILDNVEGAREKAERGELLFGTVDTWLVWKLTQGRVHVTDYTNASRTMLFNIHTKQWDDKMLEILNIPRSILPEVRNSSEIYGQTNIGGKGGVRIPVAGIAGDQQAALYGHLCVHAGQAKNTYGTGCFMLLHTGNKAITSKNGLLTTIACNAKGEPEYALEGSVFIAGASIQWLRDELKIVHDSFDSEYFAQKVTDSNGVYVVPAFTGLGAPYWDPYARGAIFGLSRGANCNHIVRATLQSIAYQTRDVLEAMQSDSGERLQYLRVDGGATNNNFLMQFQADILDVNVERPVVKEVTALGAAYLAGLATGFWKDLDELRDKARVERTFSPDSDNEKRERRYKGWKKAVKRSLEWAKEDEE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000671
EMBL· GenBank· DDBJ
ABQ99045.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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