A5UCR5 · RLMM_HAEIE

Function

function

Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.

Catalytic activity

Features

Showing features for binding site, active site.

136350100150200250300350
TypeIDPosition(s)Description
Binding site194S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site227-230S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site246S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site266S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site284S-adenosyl-L-methionine (UniProtKB | ChEBI)
Active site313Proton acceptor

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Molecular FunctionS-adenosylmethionine-dependent methyltransferase activity
Biological Processmethylation
Biological ProcessrRNA processing

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Ribosomal RNA large subunit methyltransferase M
  • EC number
  • Alternative names
    • 23S rRNA (cytidine2498-2'-O)-methyltransferase
    • 23S rRNA 2'-O-ribose methyltransferase RlmM

Gene names

    • Name
      rlmM
    • Ordered locus names
      CGSHiEE_06065

Organism names

Accessions

  • Primary accession
    A5UCR5

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00003145161-363Ribosomal RNA large subunit methyltransferase M

Interaction

Subunit

Monomer.

Structure

Family & Domains

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    363
  • Mass (Da)
    41,499
  • Last updated
    2007-07-10 v1
  • Checksum
    F7AFF406BE828F69
MNKLALYCRPGFEKEVAAEIADQASHLGVFGFARVQDNSGYVIFECYQPDEADRLARDIPFNRLIFARQMMVISGLLEDLDPADRISPIVTAFEELSQQVNFAQSSELFVETADTNEAKELSTFCRKFTVPLRQALKKQGWLSAKATQKSGQFLHCFFVKPNCCYVGYSYVDNHSPHFMGIPRLKFPADAPSRSTLKLEEAILTFIPRKEENKRLNENMIGVDLGACPGGWTYQLVKRGLFVYAVDHGKMAASLHDTGRIEHCAEDGFKFQPPKRKKVDWLVCDMVEQPSRISLLIGKWLLNGWCRETIFNLKLPMKKRYQEVILCLENLAVMLAEQNLNFEIQAKHLYHDREEITVHIALKP

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000671
EMBL· GenBank· DDBJ
ABQ98566.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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