A5PMY6 · COL12_DANRE

Function

function

Scavenger receptor that displays several functions associated with host defense. Binds to carbohydrates (By similarity).

Features

Showing features for binding site.

1720100200300400500600700
TypeIDPosition(s)Description
Binding site643Ca2+ 1 (UniProtKB | ChEBI)
Binding site645Ca2+ 1 (UniProtKB | ChEBI)
Binding site649Ca2+ 1 (UniProtKB | ChEBI)
Binding site670a carbohydrate (UniProtKB | ChEBI)
Binding site673a carbohydrate (UniProtKB | ChEBI)
Binding site673Ca2+ 3 (UniProtKB | ChEBI)
Binding site675a carbohydrate (UniProtKB | ChEBI)
Binding site675Ca2+ 3 (UniProtKB | ChEBI)
Binding site676Ca2+ 2 (UniProtKB | ChEBI)
Binding site685a carbohydrate (UniProtKB | ChEBI)
Binding site685Ca2+ 2 (UniProtKB | ChEBI)
Binding site685Ca2+ 3 (UniProtKB | ChEBI)
Binding site686Ca2+ 2 (UniProtKB | ChEBI)
Binding site697a carbohydrate (UniProtKB | ChEBI)
Binding site697Ca2+ 3 (UniProtKB | ChEBI)
Binding site698a carbohydrate (UniProtKB | ChEBI)
Binding site698Ca2+ 3 (UniProtKB | ChEBI)
Binding site710Ca2+ 1 (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcollagen trimer
Cellular Componentcollagen-containing extracellular matrix
Cellular Componentextracellular space
Cellular Componentmembrane
Molecular Functioncarbohydrate binding
Molecular Functionlow-density lipoprotein particle binding
Molecular Functionmetal ion binding
Molecular Functionpattern recognition receptor activity
Biological Processphagocytosis, recognition
Biological Processvasculogenesis

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Collectin-12

Gene names

    • Name
      colec12
    • ORF names
      si:ch211-212m21.5

Organism names

  • Taxonomic identifier
  • Strains
    • Tuebingen
    • AB
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio

Accessions

  • Primary accession
    A5PMY6
  • Secondary accessions
    • Q08CB7

Proteomes

Organism-specific databases

Subcellular Location

Features

Showing features for topological domain, transmembrane.

TypeIDPosition(s)Description
Topological domain1-37Cytoplasmic
Transmembrane38-58Helical; Signal-anchor for type II membrane protein
Topological domain59-720Extracellular

Keywords

PTM/Processing

Features

Showing features for chain, disulfide bond.

TypeIDPosition(s)Description
ChainPRO_00003186851-720Collectin-12
Disulfide bond604↔615
Disulfide bond634↔709
Disulfide bond687↔701

Keywords

Proteomic databases

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for coiled coil, region, domain, compositional bias.

TypeIDPosition(s)Description
Coiled coil95-120
Coiled coil216-267
Coiled coil377-408
Region433-576Disordered
Domain444-503Collagen-like 1
Domain510-569Collagen-like 2
Compositional bias561-576Pro residues
Domain611-710C-type lectin

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    720
  • Mass (Da)
    78,035
  • Last updated
    2007-07-10 v1
  • Checksum
    0DD184C27C37E0AC
MKDDFNDEEEVQSFGYKRFGIQEGNECTKCKNDWALRVAIALLYVLCALLTIAVAVLGYKVVQRMDNVTEGMQNYGGKITAVETDLKKLDDQTGEKSENATSELHSFKLEFQTLQKQLSDVIVKTSNNRAVLKELQLAGEDMQSGHLSLRDLLESNANVISKVNHTLNTYNSLIDGLKTETARLQSDLHVQTSEQGQNSHSISTLNFTQTQQRNLISSLQRSVEDTGQAVQKLKNDYQSLQQVARQTKADADWLREKVQNLQALAANNSLLTRSNSDSLEDVTSQLTTLSEQVQNTSTITDSHDQSLRELMDQQRDHDNATSIRFDALEARLDSNEGEMDRITGNVSFTTQLLRAISTDLNGLRTCSETVTRHSELLHGLNNSVAETRAESTELKAQQEELAVRLDKEVSSLSIVMDEMKLVDNKHSQLITNFTILQGPPGPRGPRGDKGSMGLPGKTGPKGEKGEKGAPGDAGPKGEKGPAGPPGVPGLKGPPGSRGSPGPKGSRGSGGRQGPSGEKGDPGIPGMPGRDGQPGPTGPQGPQGLRGPAGPAGLEGARGPVGPIGPPGPPGLPGLPAPPIVVPPVDPQGFVNRQVAPPPTTTPGCPPQWKGFREQCYHFSAPMESLNFDEAKERCSNLSSSMLIINDEEEQLWIKRQISGKGYFWLGLKWKPGQPDNWSHGHEAGEDCAGLIHEASWNDFFCTERIGFICERTNESKVPVL

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
A0A8M2BAJ9A0A8M2BAJ9_DANREcolec12740

Features

Showing features for sequence conflict, compositional bias.

TypeIDPosition(s)Description
Sequence conflict80in Ref. 2; AAI24304
Sequence conflict112in Ref. 2; AAI24304
Compositional bias561-576Pro residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BX927088
EMBL· GenBank· DDBJ
CAN88233.1
EMBL· GenBank· DDBJ
Genomic DNA
BC124303
EMBL· GenBank· DDBJ
AAI24304.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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