A5JYS4 · A5JYS4_CAEEL

  • Protein
    poly(ADP-ribose) glycohydrolase
  • Gene
    parg-1
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    2/5

Function

Features

Showing features for active site, binding site.

170550100150200250300350400450500550600650700
Type
IDPosition(s)Description
Active site536
Binding site539substrate
Binding site553substrate
Active site554
Active site555
Binding site594substrate

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Molecular Functionpoly(ADP-ribose) glycohydrolase activity
Biological Processcarbohydrate metabolic process
Biological Processregulation of DNA repair

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    poly(ADP-ribose) glycohydrolase
  • EC number

Gene names

    • Name
      parg-1
    • Synonyms
      pme-3
    • ORF names
      CELE_F20C5.1
      , F20C5.1

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Bristol N2
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Nematoda > Chromadorea > Rhabditida > Rhabditina > Rhabditomorpha > Rhabditoidea > Rhabditidae > Peloderinae > Caenorhabditis

Accessions

  • Primary accession
    A5JYS4

Proteomes

Organism-specific databases

PTM/Processing

Proteomic databases

Expression

Gene expression databases

Structure

Family & Domains

Features

Showing features for region, compositional bias, domain.

Type
IDPosition(s)Description
Region28-87Disordered
Compositional bias34-58Basic and acidic residues
Region102-131Disordered
Compositional bias105-128Basic and acidic residues
Region206-232Disordered
Compositional bias213-232Polar residues
Domain406-493PARG helical
Domain506-694PARG catalytic Macro

Sequence similarities

Belongs to the poly(ADP-ribose) glycohydrolase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    705
  • Mass (Da)
    80,754
  • Last updated
    2007-06-26 v1
  • Checksum
    EBB9699F0149E0C4
MSKKFIELGDPVTQDEKDYEDYVGVGFAHQVPTMKRRKLTEHGNTTESKEDPEEPKSRDVFVSSQSSDESQEDSAENPEIAKEVSENCENLTETLKISNIESLDNVTERSEHTLDNHKSTEPMEEDVNNKSNIDVAINSDEDDELVLEENNKEMRDGEQVQQDLFADDQELIEYPGIMKDTTTQLDITDSEVETAQKMEMIEETEADSTFVGEDSKNQRQSGTTSDEVDADSQINLATKTVRTSSSSFLSTVSTCEAPAKGRARMYQKELEKHVIAFTEGNLTLQPDLNKVDPDRNYRYCTIPNFPASQGKLREDNRYGPKIVLPQRWREFDSRGRRRDSYFYFKRKLDGYLKCYKTTGYFMFVGLLHNMWEFDPDITYKLPALEMYYKEMSELVGREEVLEKFARVARIAKTAEDILPERIYRLVGDVESATLSHKQCAALVARMFFARPDSPFSFCRILSSDKSICVEKLKFLFTYFDKMSMDPPDGAVSFRLTKMDKDTFNEEWKDKKLRSLPEVEFFDEMLIEDTALCTQVDFANEHLGGGVLNHGSVQEEIRFLMCPEMMVGMLLCEKMKQLEAISIVGAYVFSSYTGYGHTLKWAELQPNHSRQNTNEFRDRFGRLRVETIAIDAILFKGSKLDCQTEQLNKANIIREMKKASIGFMSQGPKFTNIPIVTGWWGCGAFNGDKPLKCMLFHSLNIEDGGE

Computationally mapped potential isoform sequences

There are 7 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
Q867X0PARG1_CAEELparg-1781
L8EC33L8EC33_CAEELparg-1782
F5GU97F5GU97_CAEELparg-1604
X5M907X5M907_CAEELparg-1779
X5LVA3X5LVA3_CAEELparg-1784
Q5WRP7Q5WRP7_CAEELparg-1625
X5M5W8X5M5W8_CAEELparg-1761

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias34-58Basic and acidic residues
Compositional bias105-128Basic and acidic residues
Compositional bias213-232Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BX284604
EMBL· GenBank· DDBJ
CAN86582.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help