A5I7P4 · SYK_CLOBH
- ProteinLysine--tRNA ligase
- GenelysS
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids504 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys)
Cofactor
Note: Binds 3 Mg2+ ions per subunit.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | aspartate-tRNA ligase activity | |
Molecular Function | ATP binding | |
Molecular Function | lysine-tRNA ligase activity | |
Molecular Function | magnesium ion binding | |
Molecular Function | nucleic acid binding | |
Molecular Function | transferase activity | |
Biological Process | aspartyl-tRNA aminoacylation | |
Biological Process | lysyl-tRNA aminoacylation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameLysine--tRNA ligase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Bacillota > Clostridia > Eubacteriales > Clostridiaceae > Clostridium
Accessions
- Primary accessionA5I7P4
- Secondary accessions
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_1000101110 | 1-504 | Lysine--tRNA ligase | |||
Sequence: MSKEDNVMNSFEEQANELMKERFQKLKELQSNGKDPFDVYKVERTHTSKEVKENYEDLEGKTVTVAGRLMSKRVHGKAGFSDIHDRYGKIQLYIKINDVGEEKLKEYKTFDIGDIISVTGTVFKTKTGETSIHITDFQLVCKSLRPLPEKWHGLKDPDLRYRQRYVDLIINQDVRDTFMKRTAIIKTMREYLDNKGFLEVETPILSPIAGGAAAKPFITHHNALNIDMYLRIATELYLKRLIVGGFEKVYEIGRNFRNEGMDIRHNPEFTVIELYEAYADYNDMMEITENMIAYICEKVLGTTKVQYEGTEIDFTPPWRRLTMVDAVREYAGVDFNTIKDDIEARTIAKEKHIEFKKELKDCTKGDVLIGLFEEFCEDKLMQPTFICDYPVENSPLTKKKRGNEAFTERFEGFVFGREVCNAYSELNDSIVQKERFMQQLKERELGDDEAYMMDDDFITSLEVGMPPTGGLGIGIDRLIMFLTDTHSIRDVILFPTMKPQPNNQ |
Interaction
Subunit
Homodimer.
Structure
Sequence
- Sequence statusComplete
- Length504
- Mass (Da)58,444
- Last updated2007-06-26 v1
- Checksum11181841BD992CC4
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP000727 EMBL· GenBank· DDBJ | ABS38115.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AM412317 EMBL· GenBank· DDBJ | CAL85079.1 EMBL· GenBank· DDBJ | Genomic DNA |