A5I5J5 · MURG_CLOBH

Function

function

Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

Catalytic activity

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site11-13UDP-N-acetyl-alpha-D-glucosamine (UniProtKB | ChEBI)
Binding site164UDP-N-acetyl-alpha-D-glucosamine (UniProtKB | ChEBI)
Binding site194UDP-N-acetyl-alpha-D-glucosamine (UniProtKB | ChEBI)
Binding site289UDP-N-acetyl-alpha-D-glucosamine (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionglycosyltransferase activity
Molecular FunctionUDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity
Molecular Functionundecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity
Biological Processcarbohydrate metabolic process
Biological Processcell division
Biological Processcell wall organization
Biological Processlipid glycosylation
Biological Processpeptidoglycan biosynthetic process
Biological Processregulation of cell shape

Keywords

Enzyme and pathway databases

Protein family/group databases

Names & Taxonomy

Protein names

  • Recommended name
    UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
  • EC number
  • Alternative names
    • Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Gene names

    • Name
      murG
    • Ordered locus names
      CBO2761, CLC_2635

Organism names

Accessions

  • Primary accession
    A5I5J5
  • Secondary accessions
    • A7G6Q8

Proteomes

Subcellular Location

Cell membrane
; Peripheral membrane protein

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_10000026341-354UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase

Structure

Family & Domains

Sequence similarities

Belongs to the glycosyltransferase 28 family. MurG subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    354
  • Mass (Da)
    39,608
  • Last updated
    2007-06-26 v1
  • Checksum
    FB1EDC889AB64A34
MKKIIMTGGGTAGHVTPNLALVPELKKLGYEIKYIGSIEGIERKIIEKEGIEYFPISSGKLRRYFDLKNFSDPFKVLKGVFQAKKIIKREKPDIVFSKGGFVTVPVVIAAHLNKIPVIAHESDITPGLANKLATPYCTRVCVTFPESVKHIKGDKAVLTGTPIRRELLEGNKLEGIKLCGFKDNKPILLIIGGSLGSKIINEIVRKNLDNILSKFNIIHICGKSNLDENLENRKGYAQFEYVNEELPDLMKASDLVISRAGANVIYELLALKKPNLLIPLSKKSSRGDQILNAASFEKSGYSLVLKEEELEDKTLIKKLNYLYENRNVYINNMSKSKMDNGVKNITELIKKYTK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000727
EMBL· GenBank· DDBJ
ABS36320.1
EMBL· GenBank· DDBJ
Genomic DNA
AM412317
EMBL· GenBank· DDBJ
CAL84322.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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