A5I1A6 · DRDI_CLOBH

Function

function

Catalyzes the isomerization of 5-deoxy-alpha-D-ribose 1-phosphate to 5-deoxy-D-ribulose 1-phosphate, as part of a 5-deoxyribose salvage pathway that recycles this toxic radical SAM enzyme by-product to mainstream metabolites.

Catalytic activity

Pathway

Carbohydrate degradation.

Features

Showing features for binding site, site, active site.

134950100150200250300
TypeIDPosition(s)Description
Binding site49-51substrate
Binding site92substrate
Site160Transition state stabilizer
Binding site199substrate
Active site240Proton donor
Binding site250-251substrate

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Molecular FunctionS-methyl-5-thioribose-1-phosphate isomerase activity
Biological ProcessL-methionine salvage from methylthioadenosine
Biological Processpentose catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    5-deoxyribose 1-phosphate isomerase
  • EC number

Gene names

    • Name
      drdI
    • Ordered locus names
      CBO1268, CLC_1306

Organism names

Accessions

  • Primary accession
    A5I1A6
  • Secondary accessions
    • A7G307

Proteomes

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00003571631-3495-deoxyribose 1-phosphate isomerase

Structure

Family & Domains

Sequence similarities

Belongs to the EIF-2B alpha/beta/delta subunits family. DrdI subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    349
  • Mass (Da)
    38,726
  • Last updated
    2007-06-26 v1
  • Checksum
    8310EDBBCF138B97
MAELLAIKWDDNRDKLILLDQTILPNKIEYIEYDTAEGVYDSIKDMIVRGAPAIGVTAAYGLYFAAKVAPEDKFENFFKYLKEKSSYLDSSRPTAVNLSWALKVMESKALENKDKDVKEIKSILREEAKRIHEEDIEICKTIGENLITLLKDGVGILTHCNAGQLATSKYGTATSPMYLAKEKGWNFKVYSDETRPRLQGSTLTALELYEAGIDVTTITDNMAAMVMSQGKIDAVIVGCDRIAANGDTANKIGTMGVSILAKYFGIPMYIAAPTPSIDINTKTGEDIPIEERNPEEVTSRFGVWTAPKGVKVYNPGFDVTPHENITAIVTEKGIVYPPFKENLKKLFEK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000727
EMBL· GenBank· DDBJ
ABS37413.1
EMBL· GenBank· DDBJ
Genomic DNA
AM412317
EMBL· GenBank· DDBJ
CAL82818.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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