A5H0D5 · A5H0D5_9RICK

Function

function

Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Pathway

Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 4/4.

Features

Showing features for binding site, site.

TypeIDPosition(s)Description
Binding site27-31substrate
Binding site77substrate
Site77Transition state stabilizer
Binding site151substrate
Binding site203substrate
Binding site317substrate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionuroporphyrinogen decarboxylase activity
Biological Processprotoporphyrinogen IX biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Uroporphyrinogen decarboxylase
  • EC number
  • Short names
    UPD
    ; URO-D

Gene names

    • Name
      hemE
    • ORF names
      E5C28_05350

Organism names

Accessions

  • Primary accession
    A5H0D5

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain22-31Uroporphyrinogen decarboxylase (URO-D)
Domain139-155Uroporphyrinogen decarboxylase (URO-D)

Sequence similarities

Belongs to the uroporphyrinogen decarboxylase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    338
  • Mass (Da)
    37,762
  • Last updated
    2007-06-12 v1
  • Checksum
    DB28768C549B3FEF
MKRSKAKIARIISQNESDEKVPIWLMRQAGRSLPEYRKAVENMNNFMEICYSTDLVTELTLQPITRFDMDAAIIFSDILIIADILGCNVNFIRGVGPIIRPIESAKDLKSLQGIESNTLPILNAIKEVRSQLPEEKSLIGFAGGPWTVGSYIIEGGSSKTFSKVLNFCPLALEEIIKKITEATIIYLIKQIEFGADVIQLFDSNAGVLKGKLFERYIIKPTKEIVSAIKSRFPNFPIIGFPRSAENLYTDYCEQTGVSAVSIDYNVPIEWAKENLKIPLQGNLNPSLLAYNKSEAIEEAKRIIDCFRGLPFIFNLGHGVLPDTPVENVAALVDLVRNY

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
DQ498881
EMBL· GenBank· DDBJ
ABF55509.1
EMBL· GenBank· DDBJ
Genomic DNA
SRKC01000036
EMBL· GenBank· DDBJ
TGB05909.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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