A5H0C9 · A5H0C9_WOLPM
- ProteinUroporphyrinogen decarboxylase
- GenehemE
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids338 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
Catalytic activity
- uroporphyrinogen III + 4 H+ = coproporphyrinogen III + 4 CO2
Pathway
Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 4/4.
Features
Showing features for binding site, site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 27-31 | substrate | |||
Binding site | 77 | substrate | |||
Site | 77 | Transition state stabilizer | |||
Binding site | 151 | substrate | |||
Binding site | 203 | substrate | |||
Binding site | 317 | substrate | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | uroporphyrinogen decarboxylase activity | |
Biological Process | protoporphyrinogen IX biosynthetic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameUroporphyrinogen decarboxylase
- EC number
- Short namesUPD ; URO-D
Gene names
Organism names
- Organism
- Strains
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Rickettsiales > Anaplasmataceae > Wolbachieae > Wolbachia
Accessions
- Primary accessionA5H0C9
Subcellular Location
Interaction
Subunit
Homodimer.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 22-31 | Uroporphyrinogen decarboxylase (URO-D) | |||
Domain | 139-155 | Uroporphyrinogen decarboxylase (URO-D) | |||
Sequence similarities
Belongs to the uroporphyrinogen decarboxylase family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length338
- Mass (Da)37,843
- Last updated2007-06-12 v1
- MD5 Checksum5351A41051299B96C82E2E483F7A78BE
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
DQ498878 EMBL· GenBank· DDBJ | ABF55503.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DQ498879 EMBL· GenBank· DDBJ | ABF55505.1 EMBL· GenBank· DDBJ | Genomic DNA |