A5EWY9 · IF2_DICNV

Function

function

One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

Features

Showing features for binding site.

1879100200300400500600700800
TypeIDPosition(s)Description
Binding site389-396GTP (UniProtKB | ChEBI)
Binding site435-439GTP (UniProtKB | ChEBI)
Binding site489-492GTP (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Molecular FunctionGTP binding
Molecular FunctionGTPase activity
Molecular Functionguanosine tetraphosphate binding
Molecular Functiontranslation initiation factor activity

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Translation initiation factor IF-2

Gene names

    • Name
      infB
    • Ordered locus names
      DNO_0029

Organism names

Accessions

  • Primary accession
    A5EWY9

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00003354661-879Translation initiation factor IF-2

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for region, compositional bias, domain.

TypeIDPosition(s)Description
Region45-216Disordered
Compositional bias51-163Basic and acidic residues
Compositional bias175-216Basic and acidic residues
Region228-293Disordered
Domain380-549tr-type G
Region389-396G1
Region414-418G2
Region435-438G3
Region489-492G4
Region525-527G5

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    879
  • Mass (Da)
    97,946
  • Last updated
    2007-06-12 v1
  • Checksum
    91A3B5B6368B4A86
MTVAELAKQLRISINRLLDVISEAGIVIHDVENDVLSPEQKVAIAGHMKQRKKQSATEKNAAKSDNKSDKNSKTGAKKTTNRRKTDARKSQSSEKKISPRELAQQLAEKKRLEQGNAQRENEEREYQEALAAEEKRQQQEEARKAKREQKEAEAIRAEEERLQMEAALQAQMQEQERIRQEKEAEEAKLNAEKELRKQQEREKRLAQEKAELERKRQEAIRDVELRESYEEEAETRFHIQSKDRNFGSKNDRSGKRAVKNGDDERSGERRNNARNNTRRRNNDNKKGKFEKPVAPISREVRIPETITVGDLAQKMSVKASELIKTMMKLGSMVTINQLLDQETAALIADEMGHRYVLLKENELEEQVMAQASENKMDVVVRAPVVTIMGHVDHGKTSLLDYIRHTRVVSGEAGGITQHIGAYRVTTERGVITFLDTPGHAAFTAMRARGANVTDIVVLVVAADDGVMPQTKEAIQHAKAANVPLIVAVNKMDKPEADPERVKSELSQEGVISEEWGGEHLFAYVSAKSGMGIDDLLEKILIQAEMLELTAPSSGVGKGVVVESRLDRGRGSVATVLVQSGVMKKGNVMLAGMEYGRIRAMLDEKGKELEEAGPSTPVEILGLSGTPNAGDDVIIVENERKAREIANFRQGKFKEIRIARQQKTKLENLFNNADGEISKVSLMIKADVQGSVEALADSLRELSTDEVAVNIIATGIGGITESDVQLALASSATIIAFNVRAEANAKKLIEEEGGDLRYYSIIYQAIDDVKAAMQGLLSPEIREEIIGLAEVRDVFRSSKFGAVAGCIVEDGLLKRHNPIRVLRNNVVIYEGELESLRRFKDDVNEVRAGTECGLGVKNYNDVRVGDQIECYERVEIERKL

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias51-163Basic and acidic residues
Compositional bias175-216Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000513
EMBL· GenBank· DDBJ
ABQ14161.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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