A5DMF7 · A5DMF7_PICGU

Function

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
FAD (UniProtKB | Rhea| CHEBI:57692 )

FMN (UniProtKB | Rhea| CHEBI:58210 )

[3Fe-4S] cluster (UniProtKB | Rhea| CHEBI:21137 )

Pathway

Amino-acid biosynthesis; L-glutamate biosynthesis via GLT pathway; L-glutamate from 2-oxoglutarate and L-glutamine (NAD+ route): step 1/1.
Energy metabolism; nitrogen metabolism.
Nitrogen metabolism.

GO annotations

AspectTerm
Molecular Function3 iron, 4 sulfur cluster binding
Molecular Functionendonuclease activity
Molecular Functionglutamate synthase activity
Molecular Functionmetal ion binding
Molecular Functionoxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
Biological Processglutamine metabolic process
Biological Processintein-mediated protein splicing
Biological ProcessL-glutamate biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    glutamate synthase (NADH)
  • EC number

Gene names

    • ORF names
      PGUG_04458

Organism names

Accessions

  • Primary accession
    A5DMF7

Proteomes

Organism-specific databases

PTM/Processing

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, region.

TypeIDPosition(s)Description
Domain45-457Glutamine amidotransferase type-2
Domain1489-1651DOD-type homing endonuclease
Region2140-2161Disordered

Sequence similarities

Belongs to the glutamate synthase family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    2,679
  • Mass (Da)
    295,787
  • Last updated
    2008-07-22 v2
  • Checksum
    7932D10D624E20BB
MSYLPHDEFETNVYSYDEVPENKSWASTLPTAKGLYNPEYEKDACGVGFTCHIKGQASHKIVSDCRNLLCNMTHRGGELNPKDGDGAGLLSSLPHKFLVREFQYHCNVTLPPLGQYGTGNVFFKKDDVVFEKSKKTFENIAASLGLRVLGWRAVPHDSSILGPASLSREPLILQPLIVLAEAFGPGSAPQEDISTDDFEKKYQRSFEKNLFILRKQSSHTIGLHNWFYICSLSNRTIVYKGQLAPNQVYAYYHDLVNADFEAHFALVHSRFSTNTFPSWDRAQPLRWAAHNGEINTLRGNKNWMRAKEGVMASELFGDELDKLYPIIEEGGSDSAAFDNVLELLVINGVLSLPEAVMVMIPEAWQNDTHIDPKKKAFYEWAACLMEPWDGPALFTFADGRYCGANLDRNGLRPCRYYVTDDDRMICASEVGVIEIEPEKILQKGRLQPGRMLLVDTKEGRIVDDRELKKSVASRFDFKSWVLANMITMNDLTEKLVSREIEVSKEVELSTDITVQSDPRLVAFGYSHEQITFVLAPMAEGNEALGSMGNDNALACISEQPKLLFDYFRQLFAQVTNPPIDPIREKIVMSLDCYVGPQGNLLEMKPDQCNRLLLKSPILSTAELINIKHIEKIYPKWSVAIIDTTFEKADGIQGYLNTIDLVCQAASKAIADNNQIIILSDRSTSATRVPISSLIATGAVHHHLVRQKQRSKVALIIETAEAREVHHACCLVGYGADAINPYLAIETLIRMNKEGLLKKEMSDEEIIKNYKNSVDAGILKVMSKMGISTLASYKGAQIFEALGVDNSVIDRCFAGTASRIKGVTFEYIAQDAFSMHERGYPNRDTVKPKGLPETGEYHWRDGGDAHINEPVAIASMQDAVRNKNEKAYETYSKKEYEAIKNCTLRGLLDFDFENSKAVPIDQVEPWTEIVRRFFTGAMSYGSISMEAHSTIAVAMNRLGGKSNTGEGGEDAARSQINANGDTMRSAIKQIASGRFGVTSYYLADADELQIKMAQGAKPGEGGELPGHKVSAEIGKTRHSTPGVGLISPPPHHDIYSIEDLKQLLYDLKCSNPRARTSVKLVSEVGVGIVAAGVAKAGSENILVSGGDGGTGAAKLTSIKYAGLPWELGLAESHQTLVLNDLRGRVVLQTDGQIRTGRDIAVAALLGAEEWGFATTPLIAMGCIMMRKCLASDTLVRTTQGLKKVKDVSVGEYLYGADNTPVLCIGANAPETGSLKEIVYEDFDSKKLVSFKCTPDHHLELVLANAAPELSGSTVTWFSSCTGEHKKQDSTFDLESIVSSFYNDLVDSDDIITFDNVCEAIDVALDEHYHRGGSDRYSEKFNGFITQIANEELKSNPEFVRNALHEAAEKFMVEDAPKNFAVTSVSVETTSVESQSVCKSSCACGGVRKIVHQFETIEEAEMAYSLLLSDVYDRVDPSFVSNGYKFQASVEALEQMCSKDILHNHLHMYRAPAEQVEPLTHSSSLPVDPYFLGLWLGEGSSDSATISTTDREVVVWLQQYVERLNKDKPAEASPLRLTKINGFKPGQQMANGFVQKVTVPTYTITSGESFTGGNWNPVYNSLKSMGLLSNKSNGIPEAYKAADLQSRLALLAGLVDSDGCYVESYNSYRFMQKSELHKKIVYDLKEMATSCGIETTDIDVSESRLYLGSSETTSAYVVYLGSGSEKLQQSLLLPRKKMVRIESCIQESTPFKVQDVANGEFRAIEVSGGKFQLDNGLQIANCHLNTCPVGIATQDPDLRKKFEGTPEHVINFFYYLANELRNIMAQLGFRTINEMVGRAEKLKVREDLRNTKNANIDLSPILTPAHTIRPGVATHCVRKQDHKLHVRIDNKLIDESEMTLAKGLPVTIDCDVVNTDRTLGTTLSYRVSKTFGEQGLPHDTIHVNAKGSAGQSFGAFLASGITLELEGDANDYIGKGLSGGRIIVYPPRESKFNAEDQIIAGNTAFFGATSGTAFIRGIAAERFAVRNSGANIVTEGTGDHGCEYMSGGRVVVLGSTGRNFAAGMCGGIAYVLDMAQDFGDKVNTQTVELSSVTDPAEIAFLRGLIEDHRHYTESEVADRILNDFNRILPRFVKVLPFDYKKVLEKEKQKAEEAKKNELSTFLKSIKEDPEADVTNGEAAKIKKGHVHRPSKASEPPVLDVEDTVTDSAAAKKPVVKLDKVRGFMKYKRRNEKYRPATERSKDWKEMSSRLTKDELKHETARCMDCGVPFCTSDTGCPISNVIPKWNELVFQDRWYDAWQRLMMTNNFPEFTGRICPAPCNGACVLGINEVPVNIKSIECAIIDHAFEQGWVKPEPPAQRTGKTVAVIGSGPAGLAAADQLNKAGHLVTVFERSDRAGGLMMYGIPNMKLDKRLVKRRTDLMAAEGVEYRCNTTVGEDISMEELKSTYDAVVFAVGSTIPRDLKIPGRELTNIKFAMELLHSNTKALLDDNLEEIRKTLAGKHVVVIGGGDTGNDCLGTSTRHGAKSVTNFELLPTPPATRPKDNPWPQWPRIFRVDYGHTEVATHYGKDPREYSILSKEFVDDGEGNVKGIKTVRVEWKRSDSGAWQMAEVPGSEEFFPADVVLLSMGFVGPDADKLEVNKTKRGTIGTLDPNGYKVGANDNVFAAGDCRRGQSLVVWGIQEGRQCAREVDNYLMGSTRLPGNGSIEQRNYKLLEEYAEKV

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CH408159
EMBL· GenBank· DDBJ
EDK40360.2
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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