A5D654 · ISPE_PELTS

Function

function

Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

Catalytic activity

Pathway

Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 3/6.

Features

Showing features for active site, binding site.

128720406080100120140160180200220240260280
TypeIDPosition(s)Description
Active site10
Binding site94-104ATP (UniProtKB | ChEBI)
Active site136

GO annotations

AspectTerm
Molecular Function4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity
Molecular FunctionATP binding
Biological Processisopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway
Biological Processterpenoid biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    4-diphosphocytidyl-2-C-methyl-D-erythritol kinase
  • EC number
  • Short names
    CMK
  • Alternative names
    • 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase

Gene names

    • Name
      ispE
    • Ordered locus names
      PTH_0096

Organism names

Accessions

  • Primary accession
    A5D654

Proteomes

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00003357361-2874-diphosphocytidyl-2-C-methyl-D-erythritol kinase

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the GHMP kinase family. IspE subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    287
  • Mass (Da)
    30,196
  • Last updated
    2007-06-12 v1
  • Checksum
    67295186D7E3212A
MVITALARAKINLTLDVLGKRPDGYHEVEMVMQSIELHDRLEFRPCAAGGISLAVEGADLPPGKENLVYRAAELLRAAGGVRAGAEIRLKKAIPVAAGLGGGSADAAAALVALNEMWNTGFSPAGLMELAEQLGSDVPFGLMGGTALARGRGERLERLFPCPPLGLVLVKPPFGVSTAEVYRAFKPGLNPKKADAQAMVRAIKKGDAADIAACLGNALEPVTVKMYPEVAEIKKKLMEAGALGALMAGSGPTVFGLTADLESARQVAARYRRTDEQILVTRTFNPRL

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AP009389
EMBL· GenBank· DDBJ
BAF58277.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp