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A5CSL4 · MIAA_CLAM3

Function

function

Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i6A).

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for binding site, site.

130720406080100120140160180200220240260280300
Type
IDPosition(s)Description
Binding site9-16ATP (UniProtKB | ChEBI)
Binding site11-16substrate
Site105Interaction with substrate tRNA
Site126Interaction with substrate tRNA

GO annotations

AspectTerm
Molecular FunctionATP binding
Molecular FunctiontRNA dimethylallyltransferase activity
Biological ProcesstRNA modification

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    tRNA dimethylallyltransferase
  • EC number
  • Alternative names
    • Dimethylallyl diphosphate:tRNA dimethylallyltransferase
      (DMAPP:tRNA dimethylallyltransferase
      ; DMATase
      )
    • Isopentenyl-diphosphate:tRNA isopentenyltransferase
      (IPP transferase
      ; IPPT
      ; IPTase
      )

Gene names

    • Name
      miaA
    • Ordered locus names
      CMM_2022

Organism names

Accessions

  • Primary accession
    A5CSL4

Proteomes

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_10000986521-307tRNA dimethylallyltransferase

Interaction

Subunit

Monomer.

Structure

Family & Domains

Sequence similarities

Belongs to the IPP transferase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    307
  • Mass (Da)
    33,300
  • Last updated
    2007-06-12 v1
  • MD5 Checksum
    AA2D8D3CDA8784CD32C9B500C4FF2B03
MIPIVAVVGATGTGKSGLSLDIADRLRAQGRVAEIVNADAMQLYRGMDIGTAKLPEAARRDVPHHMLDVLDVTAEATVAGYQGEARRVITGILGRGAVPILVGGSGLYVSSVLFDYEFPGTDPEIRQRLERELAETGPGMLHRRLRELDPAAAQRIGAHNGRRLVRALEVVEITGPQPERASAEPRPWHPARILALTLPREELVPRLDARVSGMWADGLVDEVAGLLPAGLADGVTASRAIGYAQAARQLAGELTEEEAMEETRALTRRYARRQVSWFGRYADAVRLDARDERLLEHALDALPAARP

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AM711867
EMBL· GenBank· DDBJ
CAN02085.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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