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A5CQP6 · COAD_CLAM3

Function

function

Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Pathway

Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 4/5.

Features

Showing features for binding site, site.

Type
IDPosition(s)Description
Binding site10substrate
Binding site10-11ATP (UniProtKB | ChEBI)
Binding site18ATP (UniProtKB | ChEBI)
Site18Transition state stabilizer
Binding site42substrate
Binding site78substrate
Binding site92substrate
Binding site93-95ATP (UniProtKB | ChEBI)
Binding site103ATP (UniProtKB | ChEBI)
Binding site127-133ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functionpantetheine-phosphate adenylyltransferase activity
Biological Processcoenzyme A biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phosphopantetheine adenylyltransferase
  • EC number
  • Alternative names
    • Dephospho-CoA pyrophosphorylase
    • Pantetheine-phosphate adenylyltransferase
      (PPAT
      )

Gene names

    • Name
      coaD
    • Ordered locus names
      CMM_1355

Organism names

Accessions

  • Primary accession
    A5CQP6

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_10000111241-163Phosphopantetheine adenylyltransferase

Interaction

Subunit

Homohexamer.

Structure

Family & Domains

Sequence similarities

Belongs to the bacterial CoaD family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    163
  • Mass (Da)
    17,472
  • Last updated
    2007-06-12 v1
  • MD5 Checksum
    9AC9D5936F35E00DB0C9CD2FEBF7077F
MQRIAVVPGSFDPVTLGHLDVIRRAARLYDELVVLVVHNPGKTPMLPLGERVALIERVIRDAGLPDTVRVDSWGAGLLVDYCRQVGATVLVKGVRSQLDVTYETPMALVNRDLADVETVLLLPDPAHAHVSSSLVRQVEALGGDVTPYVPAAVADALAVRRAG

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AM711867
EMBL· GenBank· DDBJ
CAN01400.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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