A4ZZA8 · A4ZZA8_PAROL

Function

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Binds 1 Mg2+ ion.
Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 2 Zn2+ ions.

Features

Showing features for binding site, active site.

147650100150200250300350400450
TypeIDPosition(s)Description
Binding site62Mg2+ (UniProtKB | ChEBI)
Binding site62Zn2+ 2 (UniProtKB | ChEBI)
Active site112Phosphoserine intermediate
Binding site173Mg2+ (UniProtKB | ChEBI)
Binding site175Mg2+ (UniProtKB | ChEBI)
Binding site332Mg2+ (UniProtKB | ChEBI)
Binding site337Zn2+ 2 (UniProtKB | ChEBI)
Binding site341Zn2+ 2 (UniProtKB | ChEBI)
Binding site378Zn2+ 2 (UniProtKB | ChEBI)
Binding site379Zn2+ 2 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentplasma membrane
Cellular Componentside of membrane
Molecular Functionalkaline phosphatase activity
Molecular Functionmetal ion binding

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Alkaline phosphatase
  • EC number

Gene names

    • Name
      alp

Organism names

Accessions

  • Primary accession
    A4ZZA8

Subcellular Location

Cell membrane
; Lipid-anchor, GPI-anchor
Membrane
; Lipid-anchor, GPI-anchor

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for signal, chain.

TypeIDPosition(s)Description
Signal1-22
ChainPRO_500763518623-476Alkaline phosphatase

Keywords

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region227-248Disordered

Sequence similarities

Belongs to the alkaline phosphatase family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    476
  • Mass (Da)
    52,293
  • Last updated
    2007-05-29 v1
  • Checksum
    C9816116007CD979
MESAKGAILVLFLLVAFASSWAKVEEENPEFWRSQARKTLQSALDRKLNTNVARNILLYLGDGMGITTYTAARILKGQLQNQTGEETVMTMDTFPSVGLAKTYSVDFQIPDSAATATAYLCGVKTNLNTIAVNAAARNGACRTQKGNEVTSILKWAKDAGKSVGIVTTTRVQHATPAASYAHSASRKWYSDANMPEAAKRDGCTDIASQLLNNTDIDVIIGGGRKYMTPRGTKDPEYPSDFSSRGKRKDGRNLINEWQSMKTGKVAHYVWNRTDFDAVDPDTTDYLMALFEPGDLRFEVERDPSMDPSIVETTEKAIRILQKNPNGFFLLVEGGRIDQAHHAGQAYMALHETVAFDYAIAKGLELTKEHETLTLVMADHSHPVTFNGYPFRGQSILGKSPLWATDMLPYTTLMYGNGPGHKLTNGTARNKLFTPPPPPVIHREHGSRFSGSAQCPPQFTAGTCTADVRSLFPCESH

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
EF512551
EMBL· GenBank· DDBJ
ABP52090.1
EMBL· GenBank· DDBJ
mRNA
FJ601913
EMBL· GenBank· DDBJ
ACM44031.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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